SCHEMBL30219263

SCHEMBL30219263

Cc1cc(C(N)=O)cc(S(C)(=O)=O)c1C

nearest known ligand 0.47

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.43
SLC9A1 P19634 1/20 0.42
PKM P14618 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9040995 0.83 PKM (0.55) SMN1; SMN2PKML3MBTL1
Hydrochloric Acid SCHEMBL9436628 0.80 SLC9A1 (0.57) SLC9A1
SCHEMBL18471225 0.80 SMN1; SMN2 (0.49) SMN1; SMN2L3MBTL1
SCHEMBL9436642 0.79 VCAM1 (0.47) SMN1; SMN2PKML3MBTL1
Hydrochloric Acid SCHEMBL9039986 0.78 SLC9A1 (0.35) SMN1; SMN2SLC9A1PKM
SCHEMBL10177915 0.78 L3MBTL1 (0.56) SMN1; SMN2SLC9A1L3MBTL1
SCHEMBL17689083 0.78 ALDH1A1 (0.51) SMN1; SMN2SLC9A1L3MBTL1
SCHEMBL31401329 0.78 ALDH1A1 (0.51) SMN1; SMN2SLC9A1L3MBTL1
SCHEMBL3283017 0.73 SLC9A1 (0.46) SMN1; SMN2SLC9A1
SCHEMBL2435832 0.72 L3MBTL1 (0.59) SLC9A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111601790-B Heteroaryl compounds as protein kinase inhibitors 福建海西新药创制股份有限公司 2023-03-31 CN claimed
CN-116715625-A Heteroaryl compounds as protein kinase inhibitors 福建海西新药创制股份有限公司 2023-09-08 CN disclosed
CN-111601790-B Heteroaryl compounds as protein kinase inhibitors 福建海西新药创制股份有限公司 2023-03-31 CN disclosed