Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | NPY2R | P49146 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 8/20 | 0.46 |
| ▸ | BRD2 | P25440 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 5/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2628020 | 0.79 | GAA (0.65) | GAANPY2RBRD4BRD2ALDH1A1 | |
| SCHEMBL16563808 | 0.76 | NPSR1 (0.48) | GAAALDH1A1KMT2APTGS2MEN1 | |
| SCHEMBL23950843 | 0.72 | GAA (0.55) | GAANPY2RBRD4BRD2ALDH1A1 | |
| SCHEMBL3163082 | 0.71 | SLC6A3 (0.44) | GAABRD4BRD2ALDH1A1TDO2 | |
| SCHEMBL12261572 | 0.70 | NPBWR1 (0.42) | GAABRD4ALDH1A1KMT2AMEN1 | |
| SCHEMBL2628017 | 0.70 | GAA (0.56) | GAANPY2RALDH1A1L3MBTL1KMT2A | |
| Hydrochloric Acid SCHEMBL6326194 | 0.70 | SLC6A3 (0.43) | GAABRD4ALDH1A1TDO2TSHR | |
| Hydrochloric Acid SCHEMBL6326189 | 0.70 | SLC6A3 (0.43) | GAABRD4ALDH1A1TDO2TSHR | |
| SCHEMBL21406490 | 0.70 | GAA (0.47) | GAANPY2RBRD4BRD2ALDH1A1 | |
| SCHEMBL4223694 | 0.68 | AKT2 (0.46) | GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4077342-B1 | PHOSPHATE DERIVATIVES OF RORGAMMA MODULATORS AND USES THEREOF | GENFIT (FR) | 2025-12-10 | — | — | EP | disclosed |
| US-12391712-B2 | Phosphate derivatives of RORgamma modulators and uses thereof | GENFIT (FR) | 2025-08-19 | — | — | US | disclosed |
| US-20230039185-A1 | PHOSPHATE DERIVATIVES OF RORGAMMA MODULATORS AND USES THEREOF | GENFIT (FR) | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12391712-B2 | Phosphate derivatives of RORgamma modulators and uses thereof | RORB, RORA, RORC | GAA 886/4885NPY2R 938/4885BRD4 2113/4885 |
| US-20230039185-A1 | PHOSPHATE DERIVATIVES OF RORGAMMA MODULATORS AND USES THEREOF | RORB, RORA, RORC | GAA 886/4885NPY2R 938/4885BRD4 2113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.