Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.64 |
| ▸ | CHUK | O15111 | 2/20 | 0.53 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 2/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31716530 | 0.90 | KIF11 (0.50) | KIF11CHUKKDM4EMETAP2MEN1 | |
| SCHEMBL6980120 | 0.90 | ACHE (0.55) | KIF11CHUKACHEKDM4EALDH1A1 | |
| SCHEMBL15380304 | 0.86 | KIF11 (0.75) | KIF11CHUKACHEKDM4EALDH1A1 | |
| SCHEMBL16552984 | 0.86 | CHUK (0.61) | KIF11CHUKMETAP2PIM3AHR | |
| SCHEMBL29764121 | 0.86 | CHUK (0.61) | KIF11CHUKMETAP2PIM3AHR | |
| SCHEMBL181890 | 0.82 | METAP2 (0.52) | CHUKMETAP2PIM3AHR | |
| SCHEMBL29387074 | 0.82 | ACHE (0.67) | KIF11CHUKACHEKDM4EALDH1A1 | |
| SCHEMBL15379639 | 0.82 | ACHE (0.67) | KIF11CHUKACHEKDM4EALDH1A1 | |
| SCHEMBL29397381 | 0.82 | METAP2 (0.52) | CHUKMETAP2PIM3AHR | |
| SCHEMBL28272924 | 0.82 | METAP2 (0.52) | CHUKMETAP2PIM3AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4125874-A1 | LIPOXYGENASE INHIBITORS | SRI International (US) | 2023-02-08 | — | — | EP | disclosed |