Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.45 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.45 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.45 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30227407 | 0.90 | KIF11 (0.64) | KIF11MEN1KMT2AFEN1METAP2 | |
| SCHEMBL1517851 | 0.87 | KIF11 (0.61) | KIF11MEN1KMT2AFEN1CCNB2 | |
| SCHEMBL29507671 | 0.87 | KIF11 (0.61) | KIF11MEN1KMT2AFEN1CCNB2 | |
| SCHEMBL29397381 | 0.87 | METAP2 (0.52) | CCNB2CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL181890 | 0.87 | METAP2 (0.52) | CCNB2CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL28272924 | 0.87 | METAP2 (0.52) | CCNB2CDK1CCNB1CCNA2CDK2 | |
| Ethane SCHEMBL29122859 | 0.82 | METAP2 (0.48) | KIF11CCNB2CDK1CCNB1CDK5 | |
| SCHEMBL10050070 | 0.80 | CHUK (0.48) | CCNB2CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL6980120 | 0.79 | ACHE (0.55) | KIF11MEN1KMT2AFEN1CDK5 | |
| SCHEMBL15380304 | 0.78 | KIF11 (0.75) | KIF11MEN1KMT2AFEN1CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025227032-A1 | METHODS FOR DEGRADATION OF CYCLIN K AND INHIBITION OF CYCLIN DEPENDENT KINASES | REMIX THERAPEUTICS INC. (US) | 2025-10-30 | — | — | WO | disclosed |