Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.75 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.75 |
| ▸ | TSHR | P16473 | 1/20 | 0.75 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.54 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30677928 | 0.86 | MAP1LC3B (0.74) | ALDH1A1MAPK1ALOX15TSHRMAP1LC3B | |
| SCHEMBL29115369 | 0.86 | MAP1LC3B (0.74) | ALDH1A1MAPK1ALOX15TSHRMAP1LC3B | |
| SCHEMBL30231429 | 0.81 | MAP1LC3B (0.55) | ALDH1A1MAPK1ALOX15TSHRMAP1LC3B | |
| SCHEMBL30227915 | 0.76 | ALDH1A1 (0.64) | ALDH1A1MAPK1ALOX15TSHRMAPT | |
| SCHEMBL4077549 | 0.75 | CA12 (0.65) | ALDH1A1MAPTHPGDCA12CA9 | |
| SCHEMBL8580581 | 0.75 | MAP1LC3B (0.80) | ALDH1A1MAPK1ALOX15TSHRMAP1LC3B | |
| SCHEMBL30228241 | 0.74 | ALDH1A1 (0.57) | ALDH1A1MAPK1ALOX15TSHRMAPT | |
| SCHEMBL30228252 | 0.74 | ALDH1A1 (0.57) | ALDH1A1MAPK1ALOX15TSHRMAPT | |
| SCHEMBL12457526 | 0.74 | ALDH1A1 (0.74) | ALDH1A1MAPK1ALOX15TSHRMAPT | |
| SCHEMBL11789592 | 0.71 | ALDH1A1 (0.46) | ALDH1A1MAPK1ALOX15TSHRMAP1LC3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023034346-A1 | CHROMEN-2-ONE MODULATORS OF POLRMT | PRETZEL THERAPEUTICS, INC. (US) | 2023-03-09 | — | — | WO | disclosed |