Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.52 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30228654 | 0.84 | KCNA3 (0.44) | ALDH1A1KCNA3MAPTTSHRALOX15 | |
| SCHEMBL30228405 | 0.82 | CA9 (0.56) | ALDH1A1KCNA3MAPTTSHRALOX15 | |
| SCHEMBL30228286 | 0.77 | KCNA3 (0.47) | ALDH1A1KCNA3MAPTTSHRALOX15 | |
| SCHEMBL30228422 | 0.76 | KCNA3 (0.46) | ALDH1A1KCNA3MAPTTSHRALOX15 | |
| SCHEMBL30228381 | 0.71 | KCNA3 (0.56) | ALDH1A1KCNA3HPGDMEN1KMT2A | |
| SCHEMBL30231625 | 0.70 | MAP1LC3B (0.74) | ALDH1A1MAPTTSHRALOX15MAPK1 | |
| Hydrochloric Acid SCHEMBL30228355 | 0.70 | KCNA3 (0.55) | ALDH1A1KCNA3HPGDMEN1KMT2A | |
| SCHEMBL30228412 | 0.70 | KCNA3 (0.62) | ALDH1A1KCNA3HPGDMEN1KMT2A | |
| SCHEMBL5691199 | 0.70 | KCNA3 (0.62) | ALDH1A1KCNA3HPGDMEN1KMT2A | |
| SCHEMBL31711138 | 0.70 | MAPT (0.42) | ALDH1A1KCNA3MAPTTSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023034346-A1 | CHROMEN-2-ONE MODULATORS OF POLRMT | PRETZEL THERAPEUTICS, INC. (US) | 2023-03-09 | — | — | WO | disclosed |