Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL1 | P55085 | 19/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5548986 | 0.79 | ADRA2A (0.42) | F2RL1 | |
| SCHEMBL6957930 | 0.78 | F2RL1 (0.39) | F2RL1 | |
| SCHEMBL9501488 | 0.78 | F2RL1 (0.46) | F2RL1 | |
| SCHEMBL4768669 | 0.78 | ALDH1A1 (0.42) | — | |
| SCHEMBL6953469 | 0.75 | F2RL1 (0.36) | F2RL1 | |
| SCHEMBL2887479 | 0.69 | — | — | |
| SCHEMBL30230708 | 0.69 | F2RL1 (0.42) | F2RL1 | |
| SCHEMBL6848050 | 0.67 | ALOX5 (0.52) | — | |
| SCHEMBL2205006 | 0.67 | F2RL1 (0.48) | F2RL1 | |
| SCHEMBL23863035 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4376840-A1 | SUBSTITUTED PYRIDINE DERIVATIVES AS SARM1 INHIBITORS | Nura Bio, Inc. (US) | 2024-06-05 | — | — | EP | claimed |
| WO-2023009663-A1 | SUBSTITUTED PYRIDINE DERIVATIVES AS SARM1 INHIBITORS | NURA BIO, INC. (US) | 2023-02-02 | — | — | WO | claimed |