Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 4/20 | 0.37 |
| ▸ | HRH1 | P35367 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30342284 | 0.81 | JAK2 (0.44) | POLBNAMPTGPR119 | |
| SCHEMBL29215634 | 0.81 | JAK2 (0.44) | POLBNAMPTGPR119 | |
| SCHEMBL28239943 | 0.77 | HRH2 (0.43) | OPRD1OPRK1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL8824367 | 0.76 | OPRD1 (0.53) | OPRD1OPRK1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL4064856 | 0.76 | OPRD1 (0.46) | OPRD1OPRK1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL30237267 | 0.75 | OPRK1 (0.48) | OPRD1OPRK1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL12520220 | 0.73 | OPRD1 (0.42) | OPRD1OPRK1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL22631375 | 0.71 | KRAS (0.43) | OPRD1OPRK1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL25232371 | 0.71 | OPRK1 (0.47) | OPRD1OPRK1SMN1; SMN2KMT2ARAB9A | |
| SCHEMBL9037444 | 0.70 | OPRD1 (0.51) | OPRD1OPRK1LMNAPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4408533-A1 | OXIMES AND THEIR USE IN TREATMENT OF GBA-RELATED DISEASES | Zevra Denmark A/S (DK) | 2024-08-07 | — | — | EP | disclosed |
| WO-2023053008-A1 | OXIMES AND THEIR USE IN TREATMENT OF GBA-RELATED DISEASES | KEMPHARM DENMARK A/S (DK) | 2023-04-06 | — | — | WO | disclosed |