Phenazopyridine

Phenazopyridine

SCHEMBL302506

Cl.I.Nc1ccc(/N=N/c2ccccc2)c(N)n1

nearest known ligand 0.96

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9A

The experimentally established mechanism targets of Phenazopyridine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.96
MEN1 O00255 8/20 0.96
KMT2A Q03164 8/20 0.96
MAPK1 P28482 6/20 0.96
TDP1 Q9NUW8 5/20 0.96
CYP3A4 P08684 3/20 0.96
SMN1; SMN2 Q16637 3/20 0.96
HBB P68871 2/20 0.96
KDM4E B2RXH2 2/20 0.96
TSHR P16473 2/20 0.96
ALOX15 P16050 2/20 0.96
SARM1 Q6SZW1 1/20 0.96
HSD17B10 Q99714 1/20 0.96
LMNA P02545 3/20 0.93
CYP1A2 P05177 2/20 0.93
HIF1A Q16665 2/20 0.93
USP2 O75604 1/20 0.93
CHRM1 P11229 1/20 0.93
CYP2C9 P11712 1/20 0.93
DRD2 P14416 1/20 0.93

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenazopyridine SCHEMBL28796595 0.98 MAPT (1.00) MAPTMEN1KMT2AMAPK1TDP1
Phenazopyridine SCHEMBL26499 0.98 MAPT (1.00) MAPTMEN1KMT2AMAPK1TDP1
Phenazopyridine SCHEMBL29392321 0.98 MAPT (1.00) MAPTMEN1KMT2AMAPK1TDP1
Phenazopyridine SCHEMBL19357 0.98 MAPT (1.00) MAPTMEN1KMT2AMAPK1TDP1
Phenazopyridine SCHEMBL215655 0.98 MAPT (1.00) MAPTMEN1KMT2AMAPK1TDP1
Phenazopyridine SCHEMBL14687482 0.98 MAPT (1.00) MAPTMEN1KMT2AMAPK1TDP1
Phenazopyridine SCHEMBL5973732 0.96 MAPT (0.96) MAPTMEN1KMT2AMAPK1TDP1
Phenazopyridine SCHEMBL301672 0.96 MAPT (0.96) MAPTMEN1KMT2AMAPK1TDP1
Phenazopyridine SCHEMBL6661856 0.96 MAPT (0.96) MAPTMEN1KMT2AMAPK1TDP1
Phenazopyridine SCHEMBL9151827 0.96 MAPT (0.96) MAPTMEN1KMT2AMAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210356472-A1 METHODS AND COMPOSITIONS FOR DETECTION AND VISUALIZATION OF OXIDATIVE STRESS-INDUCED CARBONYLATION IN CELLS THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK 2021-11-18 US claimed
EP-0586643-B1 WATCH ASSEMBLY WITH A POWER SOURCE CONSISTING OF A PHOTOVOLTAIC CELL ASULAB SA (CH) 1996-11-06 EP claimed
EP-0586640-B1 TRANSPARENT REGENERATIVE PHOTOELECTROCHEMICAL CELL ASULAB SA (CH) 1995-09-06 EP claimed
US-12565468-B2 Processes and intermediates for the preparations of Carboprost and Carboprost Tromethamine, and Carboprost Tromethamine prepared therefrom CHIROGATE INTERNATIONAL INC. (TW) 2026-03-03 US disclosed
WO-2025100466-A1 COMPLEX FOR TUMOR CHEMODYNAMIC THERAPY 国立大学法人東海国立大学機構 2025-05-15 WO disclosed
EP-4509492-A2 PROCESSES AND INTERMEDIATES FOR THE PREPARATIONS OF CARBOPROST AND CARBOPROST TROMETHAMINE, AND CARBOPROST TROMETHAMINE PREPARED THEREFROM Chirogate International Inc. (TW) 2025-02-19 EP disclosed
US-20230131316-A1 PROCESSES AND INTERMEDIATES FOR THE PREPARATIONS OF CARBOPROST AND CARBOPROST TROMETHAMINE, AND CARBOPROST TROMETHAMINE PREPARED THEREFROM CHIROGATE INTERNATIONAL INC. (TW) 2023-04-27 US disclosed
US-20230097470-A1 PROCESSES AND INTERMEDIATES FOR THE PREPARATIONS OF CARBOPROST AND CARBOPROST TROMETHAMINE, AND CARBOPROST TROMETHAMINE PREPARED THEREFROM CHIROGATE INTERNATIONAL INC. (TW) 2023-03-30 US disclosed
EP-4140982-A2 PROCESSES AND INTERMEDIATES FOR THE PREPARATIONS OF CARBOPROST AND CARBOPROST TROMETHAMINE, AND CARBOPROST TROMETHAMINE PREPARED THEREFROM Chirogate International Inc. (TW) 2023-03-01 EP disclosed
US-20210356472-A1 METHODS AND COMPOSITIONS FOR DETECTION AND VISUALIZATION OF OXIDATIVE STRESS-INDUCED CARBONYLATION IN CELLS THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK 2021-11-18 US disclosed
US-10465073-B2 Organic dye for dye-sensitized solar cell ENI S.P.A. (IT) 2019-11-05 US disclosed
EP-1507307-A1 PHOTOELECTRIC CONVERSION DEVICE Hitachi Maxell, Ltd. (JP) 2005-02-16 EP disclosed
US-20040256002-A1 Organic dye, photoelectric transducing material, semiconductor electrode, and photoelectric transducing device MITSUBISHI PAPER MILLS LTD. (JP) 2004-12-23 US disclosed
US-20040248787-A1 fusion protein comprising a PTD (protein transduction domain) and an MITF (microphthalmia-associated transcripution factor) variant as an active ingredient with a His tag MITSUBISHI PHARMA CORPORATION (JP) 2004-12-09 US disclosed
US-20040238826-A1 Photoelectric conversion device PANASONIC ELECTRIC WORKS CO., LTD. (JP) 2004-12-02 US disclosed
EP-1410802-A1 CELL DEATH INDUCERS FOR MAST CELLS Mitsubishi Pharma Corporation (JP) 2004-04-21 EP disclosed
US-5681790-A MIXED OXIDE OXIDATION CATALYST CONTAINING A QUATERNARY AMMONIUM TEMPLATE SAMSUNG GENERAL CHEMICALS CO., LTD. (KR) 1997-10-28 US disclosed
EP-0083096-B1 PRODUCTION OF URETHANE COMPOUNDS Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1987-02-25 EP disclosed
US-4621149-A PLATINUM GROUP METAL HALOGEN OR HALOGEN COMPOUND ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1986-11-04 US disclosed
EP-0083096-A2 Production of urethane compounds Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1983-07-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230097470-A1 PROCESSES AND INTERMEDIATES FOR THE PREPARATIONS OF CARBOPROST AND CARBOPROST TROMETHAMINE, AND CARBOPROST TROMETHAMINE PREPARED THEREFROM PTGES, PTGES2, PTGIS MAPT 3267/4885MEN1 4364/4885KMT2A 4479/4885
US-20230131316-A1 PROCESSES AND INTERMEDIATES FOR THE PREPARATIONS OF CARBOPROST AND CARBOPROST TROMETHAMINE, AND CARBOPROST TROMETHAMINE PREPARED THEREFROM PTGES, PTGES2, PTGIS MAPT 3267/4885MEN1 4364/4885KMT2A 4479/4885
US-12565468-B2 Processes and intermediates for the preparations of Carboprost and Carboprost Tromethamine, and Carboprost Tromethamine prepared therefrom PGF, PTGIS, PTGS1 MAPT 4304/4885MEN1 4136/4885KMT2A 1804/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.