Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17740977 | 1.00 | ALOX15 (0.38) | ALOX15LMNARAB9AMAPTALOX12 | |
| SCHEMBL17429524 | 0.84 | MAPT (0.35) | ALOX15LMNARAB9AMAPTALOX12 | |
| SCHEMBL17429601 | 0.84 | ALDH1A1 (0.37) | ALOX15LMNARAB9AMAPTALOX12 | |
| SCHEMBL17429591 | 0.81 | HTT (0.41) | ALOX15LMNAMAPTALOX12HPGD | |
| SCHEMBL17740976 | 0.80 | LMNA (0.54) | ALOX15LMNARAB9AMAPTALOX12 | |
| SCHEMBL28227556 | 0.73 | AKR1C4 (0.39) | RAB9AMAPTNPC1KDM4ECA12 | |
| SCHEMBL24314179 | 0.69 | C1S (0.45) | ALOX15LMNARAB9AMAPTALOX12 | |
| SCHEMBL17204756 | 0.69 | ALOX15 (0.43) | ALOX15LMNARAB9AMAPTALOX12 | |
| SCHEMBL29661155 | 0.67 | PTGDR2 (0.46) | LMNAMAPTKDM4EHPGDALDH1A1 | |
| SCHEMBL1758414 | 0.67 | PTGDR2 (0.46) | LMNAMAPTKDM4EHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115806493-B | Method for synthesizing epstein chiral intermediate by asymmetric hydrogenation | 南京工业大学 | 2024-03-22 | — | — | CN | claimed |
| CN-115806493-A | Method for synthesizing chiral ebavir intermediate by asymmetric hydrogenation | 南京工业大学 | 2023-03-17 | — | — | CN | claimed |
| CN-115806493-B | Method for synthesizing epstein chiral intermediate by asymmetric hydrogenation | 南京工业大学 | 2024-03-22 | — | — | CN | disclosed |
| CN-115806493-B | Method for synthesizing epstein chiral intermediate by asymmetric hydrogenation | 南京工业大学 | 2024-03-22 | — | — | CN | disclosed |
| CN-115806493-A | Method for synthesizing chiral ebavir intermediate by asymmetric hydrogenation | 南京工业大学 | 2023-03-17 | — | — | CN | disclosed |
| CN-115806493-A | Method for synthesizing chiral ebavir intermediate by asymmetric hydrogenation | 南京工业大学 | 2023-03-17 | — | — | CN | disclosed |