SCHEMBL30254757

SCHEMBL30254757

C[C@@H](O)[C@@H](C(=O)O)N(C(=O)OCc1ccccc1)C(=O)[C@@H](N)CO

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC15A1 P46059 2/20 0.40
ALDH1A1 P00352 3/20 0.40
LMNA P02545 1/20 0.40
POLB P06746 1/20 0.40
HSD17B10 Q99714 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ABCB1 P08183 1/20 0.38
SLC1A1 P43005 4/20 0.37
SLC1A3 P43003 3/20 0.37
SLC1A2 P43004 2/20 0.37
MEN1 O00255 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
KMT2A Q03164 1/20 0.37
CTSL P07711 3/20 0.37
CTSS P25774 3/20 0.37
CTSB P07858 2/20 0.37
CTSK P43235 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11433447 0.82 SLC1A1 (0.41) SLC15A1ALDH1A1SLC1A1SLC1A3CTSL
SCHEMBL7275440 0.82 SLC15A1 (0.47) SLC15A1ALDH1A1LMNAPOLBHSD17B10
SCHEMBL7420644 0.81 ANPEP (0.43) SLC15A1ALDH1A1LMNAPOLBHSD17B10
SCHEMBL10909146 0.77 CTSK (0.40) SLC15A1SLC1A1SLC1A3SLC1A2CTSL
SCHEMBL6378351 0.77 ABCB1 (0.53) SLC15A1ALDH1A1LMNAPOLBHSD17B10
SCHEMBL21066054 0.77 ABCB1 (0.53) SLC15A1ALDH1A1LMNAPOLBHSD17B10
SCHEMBL6378348 0.77 ABCB1 (0.53) SLC15A1ALDH1A1LMNAPOLBHSD17B10
SCHEMBL5065711 0.76 ALDH1A1 (0.50) SLC15A1ALDH1A1LMNAPOLBHSD17B10
SCHEMBL16595718 0.76 ALDH1A1 (0.44) SLC15A1ALDH1A1L3MBTL1ABCB1SLC1A1
SCHEMBL11801400 0.76 SLC15A1 (0.44) SLC15A1ALDH1A1LMNAPOLBHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4551696-A2 MODIFIED CRISPR-CAS EFFECTOR POLYPEPTIDES AND METHODS OF USE THEREOF The Regents of the University of California (US) 2025-05-14 EP disclosed
EP-4514958-A1 MUCIN-ACTIVE PROTEASES AND METHODS OF USE The Board of Trustees of the Leland Stanford Junior University (US) 2025-03-05 EP disclosed
WO-2024011176-A2 MODIFIED CRISPR-CAS EFFECTOR POLYPEPTIDES AND METHODS OF USE THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-01-11 WO disclosed
WO-2023212733-A1 MUCIN-ACTIVE PROTEASES AND METHODS OF USE THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2023-11-02 WO disclosed
WO-2022261758-A9 HEPATITIS C VIRUS IMMUNOGENIC COMPOSITIONS AND METHODS OF USE THEREOF AURORA VACCINES, INC. (CA) 2023-02-23 WO disclosed