Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A1 | P46059 | 3/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | LAP3 | P28838 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.39 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7420644 | 0.89 | ANPEP (0.43) | SLC15A1ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL3798156 | 0.86 | SLC6A2 (0.42) | SLC15A1ALPIPKMPTGS1XIAP | |
| SCHEMBL11801400 | 0.86 | SLC15A1 (0.44) | SLC15A1ALPIPKMPTGS1XIAP | |
| SCHEMBL5065711 | 0.86 | ALDH1A1 (0.50) | SLC15A1ALDH1A1ABCB1LMNAPOLB | |
| SCHEMBL7292946 | 0.84 | SLC15A1 (0.50) | SLC15A1ALPIPKMPTGS1XIAP | |
| SCHEMBL28790921 | 0.84 | SLC15A1 (0.50) | SLC15A1ALPIPKMPTGS1XIAP | |
| SCHEMBL7604639 | 0.83 | SLC15A1 (0.43) | SLC15A1ALPIPKMPTGS1XIAP | |
| SCHEMBL10443784 | 0.83 | SLC15A1 (0.46) | SLC15A1ALPIPKMPTGS1XIAP | |
| SCHEMBL7365482 | 0.82 | CTSB (0.43) | ALDH1A1ABCB1HSD17B10CTSB | |
| SCHEMBL8111386 | 0.82 | ALDH1A1 (0.47) | SLC15A1ALDH1A1ABCB1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376040-A2 | N-phosphinyl di-and tripeptides as renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1990-07-04 | — | — | EP | disclosed |