Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.43 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.43 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 3/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7275440 | 0.89 | SLC15A1 (0.47) | ANPEPRNPEPDNPEPSLC15A1CTSB | |
| SCHEMBL27809385 | 0.85 | ANPEP (0.48) | ANPEPRNPEPDNPEPSLC15A1CTSK | |
| SCHEMBL5065711 | 0.85 | ALDH1A1 (0.50) | SLC15A1CTSKCTSLCTSBCTSS | |
| SCHEMBL28518732 | 0.83 | ANPEP (0.53) | ANPEPRNPEPDNPEPSLC15A1SLC1A1 | |
| SCHEMBL724023 | 0.82 | CTSK (0.44) | ANPEPRNPEPDNPEPSLC15A1CTSK | |
| SCHEMBL1014662 | 0.82 | CTSB (0.44) | ANPEPRNPEPDNPEPCTSKCTSL | |
| SCHEMBL27715040 | 0.82 | ANPEP (0.40) | ANPEPRNPEPDNPEPSLC15A1CTSK | |
| SCHEMBL8111386 | 0.81 | ALDH1A1 (0.47) | SLC15A1CTSKSLC1A1SLC1A3ALDH1A1 | |
| SCHEMBL27799677 | 0.81 | ANPEP (0.45) | ANPEPRNPEPDNPEPSLC15A1CTSK | |
| SCHEMBL27473269 | 0.81 | ANPEP (0.45) | ANPEPRNPEPDNPEPSLC15A1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998025949-A1 | SUBSTITUTED 5-AMINO-1,3,4-THIADIAZOLE-2-THIONES | PROSCRIPT, INC. (US) | 1998-06-18 | — | — | WO | disclosed |