Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 3/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3031090 | 0.89 | LMNA (0.46) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL3036907 | 0.81 | — | — | |
| SCHEMBL10963604 | 0.75 | ALDH1A1 (0.49) | MAPTALDH1A1APAF1LMNAMEN1 | |
| SCHEMBL3039544 | 0.73 | MAPT (0.40) | MAPTALDH1A1L3MBTL1POLBCA1 | |
| SCHEMBL3036155 | 0.67 | POLB (0.53) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7524303 | 0.66 | — | — | |
| SCHEMBL23312214 | 0.66 | MAPT (0.37) | MAPTALDH1A1APAF1LMNAMEN1 | |
| SCHEMBL24849580 | 0.66 | PDCD4 (0.39) | CA1CA9GPR84 | |
| SCHEMBL28362540 | 0.66 | MAPT (0.88) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL24023289 | 0.66 | PDCD4 (0.36) | CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101801913-B | Method for producing 4-aminobut-2-enolides | BAYER CROPSCIENCE AG | 2014-06-11 | — | — | CN | disclosed |
| EP-2203410-B1 | METHOD FOR PRODUCING 4-AMINOBUT-2-ENOLIDES | BAYER CROPSCIENCE AG (DE) | 2014-03-26 | — | — | EP | disclosed |
| EP-2253610-B1 | Method for manufacturing of enaminocarbonyl-compounds and their use in preparing 4-aminobut-2-enolids | BAYER CROPSCIENCE AG (DE) | 2013-11-20 | — | — | EP | disclosed |
| US-8487112-B2 | Method for producing 4-aminobut-2-enolides | BAYER CROPSCIENCE AG (DE) | 2013-07-16 | — | — | US | disclosed |
| EP-2253610-A1 | Method for manufacturing 4-aminobut-2-enolids | Bayer CropScience AG (DE) | 2010-11-24 | — | — | EP | disclosed |
| US-20100204480-A1 | METHOD FOR PRODUCING 4-AMINOBUT-2-ENOLIDES | BAYER CROPSCIENCE (DE) | 2010-08-12 | — | — | US | disclosed |
| EP-2203410-A1 | METHOD FOR PRODUCING 4-AMINOBUT-2-ENOLIDES | Bayer CropScience AG (DE) | 2010-07-07 | — | — | EP | disclosed |
| WO-2009036898-A1 | METHOD FOR PRODUCING 4-AMINOBUT-2-ENOLIDES | BAYER CROPSCIENCE AG (DE) | 2009-03-26 | — | — | WO | disclosed |
| EP-2039678-A1 | Method for manufacturing 4-aminobut-2-enolids | Bayer CropScience AG (DE) | 2009-03-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204480-A1 | METHOD FOR PRODUCING 4-AMINOBUT-2-ENOLIDES | CYP4B1, TUBB4B, EIF4B | MAPT 2689/4885ALDH1A1 468/4885APAF1 3828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.