SCHEMBL24849580

SCHEMBL24849580

CCCCCCC(CCCCCC)C1=CC(=O)OC1

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PDCD4 Q53EL6 4/20 0.39
NR1I2 O75469 1/20 0.35
CA1 P00915 1/20 0.34
CA9 Q16790 1/20 0.34
DUSP3 P51452 1/20 0.33
ACHE P22303 1/20 0.31
BACE1 P56817 1/20 0.31
GPR84 Q9NQS5 3/20 0.31
FDPS P14324 3/20 0.31
FFAR1 O14842 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24023289 0.97 PDCD4 (0.36) PDCD4NR1I2CA1CA9DUSP3
SCHEMBL7296440 0.85 PDCD4 (0.41) PDCD4DUSP3GPR84FFAR1
SCHEMBL7294647 0.78 GLS2 (0.44) PDCD4
SCHEMBL7293103 0.74 PDCD4 (0.40) PDCD4
SCHEMBL9631359 0.68 NR1I2 (0.36) PDCD4NR1I2
SCHEMBL24376718 0.66 DUSP3 (0.42) PDCD4DUSP3GPR84FDPSFFAR1
SCHEMBL6911323 0.65 DNM1 (0.37) NR1I2GPR84FDPS
SCHEMBL19374387 0.64 GPR84 (0.40) NR1I2GPR84FDPSFFAR1
SCHEMBL9631580 0.63 LMNA (0.35) NR1I2GPR84
SCHEMBL3462845 0.63 LMNA (0.35) NR1I2GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230002436-A1 MODIFIED NUCLEOTIDES AND USES THEREOF FIRST-CITIZENS BANK & TRUST COMPANY 2023-01-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230002436-A1 MODIFIED NUCLEOTIDES AND USES THEREOF NUDT1, RNMT, ADAR PDCD4 4419/4885NR1I2 4826/4885CA1 4657/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.