Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PLEC | Q15149 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9027053 | 0.89 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1MAPTNPSR1ATM | |
| SCHEMBL5661565 | 0.85 | MAPT (0.49) | ALDH1A1L3MBTL1MAPTNPSR1ATM | |
| SCHEMBL30079604 | 0.83 | L3MBTL1 (0.60) | ALDH1A1L3MBTL1MAPTNPSR1ATM | |
| SCHEMBL695757 | 0.83 | L3MBTL1 (0.60) | ALDH1A1L3MBTL1MAPTNPSR1ATM | |
| SCHEMBL13875098 | 0.83 | HTR1A (0.46) | ALDH1A1TDP1HTR1ADRD2 | |
| SCHEMBL4262567 | 0.83 | L3MBTL1 (0.60) | ALDH1A1L3MBTL1MAPTNPSR1ATM | |
| SCHEMBL7759613 | 0.83 | CYP1A2 (0.53) | ALDH1A1L3MBTL1MAPTNPSR1ATM | |
| SCHEMBL24808599 | 0.82 | MAPT (0.50) | L3MBTL1MAPTNPSR1MEN1THRB | |
| SCHEMBL4174956 | 0.82 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1MAPTNPSR1ATM | |
| SCHEMBL10335287 | 0.82 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1MAPTNPSR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109970760-B | ACC inhibitors and uses thereof | 吉利德阿波罗公司 | 2022-04-26 | — | — | CN | disclosed |
| EP-3628320-B1 | ACC INHIBITORS AND USES THEREOF | GILEAD APOLLO LLC (US) | 2022-03-16 | — | — | EP | disclosed |
| CN-112955421-A | Method for dehydrating organic solvent and method for purifying organic solvent | 日本瑞翁株式会社 | 2021-06-11 | — | — | CN | disclosed |
| CN-112189002-A | Method for purifying solvent | 日本瑞翁株式会社 | 2021-01-05 | — | — | CN | disclosed |
| CN-107532017-B | Stripping solvent composition, stripping method and cleaning solvent composition | 日本瑞翁株式会社 | 2020-11-06 | — | — | CN | disclosed |
| WO-2020195454-A1 | METHOD FOR DEHYDRATING ORGANIC SOLVENT AND METHOD FOR PURIFYING ORGANIC SOLVENT | 日本ゼオン株式会社 | 2020-10-01 | — | — | WO | disclosed |
| US-20200102323-A1 | ACC INHIBITORS AND USES THEREOF | SCHRÖDINGER, INC. | 2020-04-02 | — | — | US | disclosed |
| US-20200102323-A1 | ACC INHIBITORS AND USES THEREOF | SCHRÖDINGER, INC. | 2020-04-02 | — | — | US | disclosed |
| EP-3628320-A1 | ACC INHIBITORS AND USES THEREOF | Gilead Apollo, LLC (US) | 2020-04-01 | — | — | EP | disclosed |
| WO-2020044825-A1 | METHOD FOR SOLVENT PURIFICATION | 日本ゼオン株式会社 | 2020-03-05 | — | — | WO | disclosed |
| WO-1995028640-A1 | COMPLEX COMBINATORIAL CHEMICAL LIBRARIES ENCODED WITH TAGS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1995-10-26 | — | — | WO | disclosed |
| EP-0406745-B1 | Antibiotic GE 2270 factors A1, A2, A3 and H | LEPETIT SPA (IT) | 1995-01-25 | — | — | EP | disclosed |
| US-5139778-A | ANTIBIOTIC GE 2270 FACTORS A1, A2, A3 AND H | GRUPPO LEPETIT SPA (IT) | 1992-08-18 | — | — | US | disclosed |
| EP-0146053-B1 | CHEMICAL PROCESS FOR PREPARING ANTIBIOTIC L 17392 (DEGLUCOTEICOPLANIN) AND ITS SALTS | GRUPPO LEPETIT S.p.A. (IT) | 1991-12-27 | — | — | EP | disclosed |
| EP-0240609-B1 | ANTIBIOTIC A 40926 N-ACYLAMINOGLUCURONYL AGLYCONS AND ANTIBIOTIC A 40926 AGLYCON | GRUPPO LEPETIT S.p.A. (IT) | 1991-12-04 | — | — | EP | disclosed |
| EP-0406745-A1 | Antibiotic GE 2270 factors A1, A2, A3 and H | GRUPPO LEPETIT S.p.A. (IT) | 1991-01-09 | — | — | EP | disclosed |
| US-4868171-A | Antibiotic A 40926 N-acylaminoglucuronyl aglycons and antiobiotic A 40926 aglycon | GRUPPO LEPETIT S.P.A. (IT) | 1989-09-19 | — | — | US | disclosed |
| EP-0240609-A2 | Antibiotic A 40926 N-acylaminoglucuronyl aglycons and antibiotic A 40926 aglycon | GRUPPO LEPETIT S.p.A. (IT) | 1987-10-14 | — | — | EP | disclosed |
| US-4629781-A | STRONG ACIDOLYSIS CONTROLLED BY THE USE OF SOLVENT, ACID, CONCENTRATION AND HEATING | GRUPPO LEPETIT S.P.A. (IT) | 1986-12-16 | — | — | US | disclosed |
| EP-0146053-A2 | Chemical process for preparing antibiotic L 17392 (Deglucoteicoplanin) and its salts | GRUPPO LEPETIT S.p.A. (IT) | 1985-06-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200102323-A1 | ACC INHIBITORS AND USES THEREOF | ACACA, ACACB, ACAT2 | ALDH1A1 104/4885L3MBTL1 2864/4885MAPT 2490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.