Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | LGMN | Q99538 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31333625 | 0.94 | PDE3B (0.39) | PDE3BPDE3ATP53CREBBPKMT2A | |
| SCHEMBL31334925 | 0.91 | GRIN1 (0.43) | TP53KMT2AHTR1ASLC6A2SLC6A3 | |
| SCHEMBL24794177 | 0.82 | ALDH1A1 (0.50) | HTR1ASLC6A2SLC6A3 | |
| SCHEMBL31333413 | 0.80 | ENPP2 (0.47) | HTR1ASLC6A2SLC6A3 | |
| SCHEMBL31334672 | 0.80 | GRIN1 (0.40) | HTR1ASLC6A2SLC6A3 | |
| SCHEMBL24793649 | 0.79 | JAK1 (0.42) | CREBBPKMT2A | |
| SCHEMBL24794739 | 0.79 | ENPP2 (0.45) | KMT2A | |
| SCHEMBL29709766 | 0.79 | ENPP2 (0.45) | KMT2A | |
| SCHEMBL30258792 | 0.78 | PDE3B (0.43) | PDE3BPDE3ALGMN | |
| SCHEMBL31334601 | 0.78 | CKS1B (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023059792-A1 | CORONAVIRUS NON-STRUCTURAL PROTEIN 3 DEGRADING COMPOUNDS | C4 THRAPEUTICS, INC. (US) | 2023-04-13 | — | — | WO | disclosed |