Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.43 |
| ▸ | LGMN | Q99538 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31334578 | 0.94 | OPRM1 (0.41) | PDE3BPDE3ALGMNHSD17B10AURKA | |
| SCHEMBL27166330 | 0.83 | GPR119 (0.50) | PDK2GPR119MAPT | |
| SCHEMBL21069488 | 0.82 | MAPT (0.50) | PDK2GPR119MAPT | |
| SCHEMBL26102409 | 0.81 | SPR (0.36) | GPR119BRPF1BRD4 | |
| SCHEMBL30289116 | 0.80 | NR1H2 (0.50) | — | |
| SCHEMBL30289414 | 0.80 | OPRM1 (0.49) | — | |
| SCHEMBL26206220 | 0.79 | HTR1A (0.42) | — | |
| SCHEMBL30258401 | 0.78 | PDE3B (0.43) | PDE3BPDE3ALGMN | |
| SCHEMBL22502517 | 0.77 | HTR7 (0.41) | — | |
| SCHEMBL21070672 | 0.77 | PDE3B (0.33) | PDE3BPDE3APDK2GPR119BRPF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023059792-A1 | CORONAVIRUS NON-STRUCTURAL PROTEIN 3 DEGRADING COMPOUNDS | C4 THRAPEUTICS, INC. (US) | 2023-04-13 | — | — | WO | disclosed |