Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 5/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31333413 | 0.87 | ENPP2 (0.47) | HTR1ASLC6A2SLC6A3ENPP2 | |
| SCHEMBL31333569 | 0.87 | ENPP2 (0.38) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL31334470 | 0.87 | DRD2 (0.46) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL31334685 | 0.85 | TGFBR1 (0.46) | HTR1ASLC6A2SLC6A3ENPP2KCNH2 | |
| SCHEMBL31334925 | 0.81 | GRIN1 (0.43) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL30258401 | 0.80 | PDE3B (0.43) | HTR1ASLC6A2SLC6A3 | |
| SCHEMBL31333449 | 0.78 | CRBN (0.43) | — | |
| SCHEMBL31334601 | 0.77 | CKS1B (0.42) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL24794177 | 0.75 | ALDH1A1 (0.50) | HTR1ASLC6A2SLC6A3 | |
| SCHEMBL31333625 | 0.75 | PDE3B (0.39) | HTR1ASLC6A2SLC6A3ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |