SCHEMBL31333413

SCHEMBL31333413

CC(C)(C)OC(=O)N1CCN(CC2CCN(c3ccc4[nH]c(=O)oc4c3)CC2)CC1

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 3/20 0.47
CNR1 P21554 1/20 0.44
GPR119 Q8TDV5 7/20 0.44
TGFBR1 P36897 2/20 0.44
VCP P55072 1/20 0.43
DDB1 Q16531 1/20 0.43
CRBN Q96SW2 1/20 0.43
HTR1A P08908 1/20 0.42
SLC6A2 P23975 1/20 0.42
SLC6A3 Q01959 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31334685 0.96 TGFBR1 (0.46) ENPP2CNR1GPR119TGFBR1DDB1
SCHEMBL24794177 0.87 ALDH1A1 (0.50) GPR119DDB1CRBNHTR1ASLC6A2
SCHEMBL31334672 0.87 GRIN1 (0.40) ENPP2HTR1ASLC6A2SLC6A3
SCHEMBL31334470 0.85 DRD2 (0.46) ENPP2HTR1ASLC6A2SLC6A3
SCHEMBL31333569 0.84 ENPP2 (0.38) ENPP2HTR1ASLC6A2SLC6A3
SCHEMBL29709766 0.82 ENPP2 (0.45) ENPP2
SCHEMBL24794739 0.82 ENPP2 (0.45) ENPP2
SCHEMBL30258401 0.80 PDE3B (0.43) HTR1ASLC6A2SLC6A3
SCHEMBL31334925 0.79 GRIN1 (0.43) ENPP2HTR1ASLC6A2SLC6A3
SCHEMBL24793630 0.79 ATXN2 (0.48) ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed