Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28980080 | 0.86 | NPC1 (0.44) | CA2CA4CA5AKMT2ATSHR | |
| SCHEMBL4760518 | 0.86 | LMNA (0.51) | CA2CA4CA5AKMT2ATSHR | |
| SCHEMBL30265999 | 0.82 | NPC1 (0.50) | TSHRALDH1A1CES2CES1 | |
| SCHEMBL28980070 | 0.82 | ALDH1A1 (0.47) | KMT2ATSHRGAAALDH1A1MEN1 | |
| SCHEMBL30266249 | 0.82 | RAB9A (0.48) | KMT2AL3MBTL1GAACES2CES1 | |
| SCHEMBL28980081 | 0.82 | RAB9A (0.48) | KMT2AL3MBTL1GAACES2CES1 | |
| SCHEMBL28980062 | 0.82 | CES2 (0.51) | CA2KMT2AALOX15GAAALDH1A1 | |
| SCHEMBL28437444 | 0.79 | CES2 (0.48) | KMT2AALOX15ALDH1A1CES2CES1 | |
| SCHEMBL14198464 | 0.78 | ESR1 (0.45) | CA2CA4CA5AKMT2ATSHR | |
| SCHEMBL29421945 | 0.78 | CA2 (0.52) | CA2CA4CA5AKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117362339-A | Preparation and application of organic phosphine oxide compound | 浙江扬帆新材料股份有限公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-115724887-A | Process for the synthesis of chiral alpha-phosphorus compounds | 武汉大学 | 2023-03-03 | — | — | CN | disclosed |