Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 4/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.36 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.36 |
| ▸ | MERTK | Q12866 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.33 |
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.32 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30299292 | 0.81 | HRH3 (0.32) | HRH3 | |
| SCHEMBL30299299 | 0.81 | HRH3 (0.33) | HRH3 | |
| SCHEMBL30299283 | 0.79 | L3MBTL3 (0.54) | L3MBTL3L3MBTL1 | |
| SCHEMBL30299323 | 0.79 | NPY2R (0.41) | HRH3L3MBTL3L3MBTL1 | |
| SCHEMBL29929683 | 0.78 | AXL (0.40) | AXLEGFRHRH3L3MBTL3L3MBTL1 | |
| SCHEMBL30299305 | 0.78 | ALDH1A1 (0.38) | HRH3L3MBTL3L3MBTL1 | |
| SCHEMBL30299390 | 0.78 | PDCD1 (0.38) | ALKHRH3L3MBTL3L3MBTL1 | |
| SCHEMBL29928123 | 0.78 | AXL (0.39) | AXLEGFRHRH3L3MBTL3L3MBTL1 | |
| SCHEMBL30299294 | 0.76 | L3MBTL3 (0.47) | HRH3L3MBTL3L3MBTL1 | |
| SCHEMBL30266550 | 0.76 | AXL (0.34) | AXLAURKAEGFRRETMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4132652-A1 | AXL INHIBITORS FOR ANTIVIRAL THERAPY | BerGenBio ASA (NO) | 2023-02-15 | — | — | EP | disclosed |