Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.38 |
| ▸ | L3MBTL3 | Q96JM7 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30090686 | 0.92 | EML4 (0.39) | — | |
| SCHEMBL30299323 | 0.88 | NPY2R (0.41) | ALDH1A1L3MBTL3L3MBTL1HRH3MBTD1 | |
| SCHEMBL29929683 | 0.87 | AXL (0.40) | ALDH1A1L3MBTL3L3MBTL1HRH3MBTD1 | |
| SCHEMBL30299390 | 0.86 | PDCD1 (0.38) | ALDH1A1L3MBTL3L3MBTL1HRH3PDCD1 | |
| SCHEMBL29928123 | 0.86 | AXL (0.39) | ALDH1A1L3MBTL3L3MBTL1HRH3PDCD1 | |
| SCHEMBL30299396 | 0.85 | NOTUM (0.36) | L3MBTL3L3MBTL1HRH3MBTD1NPY2R | |
| SCHEMBL30299345 | 0.85 | AXL (0.38) | ALDH1A1L3MBTL3L3MBTL1HRH3MBTD1 | |
| SCHEMBL30299340 | 0.82 | OPRK1 (0.37) | L3MBTL3L3MBTL1HRH3 | |
| SCHEMBL30299283 | 0.82 | L3MBTL3 (0.54) | L3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL30299368 | 0.81 | GAA (0.38) | ALDH1A1MEN1MAPTKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116075303-A | Method of selecting patients treated with a combination of an AXL inhibitor and an immune checkpoint modulator | 卑尔根生物股份公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-115916344-A | AXL inhibitors for antiviral therapy | 卑尔根生物股份公司 | 2023-04-04 | — | — | CN | disclosed |