Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SMO | Q99835 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30276325 | 0.81 | AXL (0.36) | HRH3 | |
| SCHEMBL30299363 | 0.77 | HRH3 (0.41) | HRH3HRH1 | |
| SCHEMBL30090686 | 0.75 | EML4 (0.39) | — | |
| SCHEMBL30299333 | 0.74 | MAP3K14 (0.33) | — | |
| SCHEMBL30090486 | 0.74 | KCNH2 (0.39) | — | |
| SCHEMBL29929746 | 0.73 | QDPR (0.38) | — | |
| SCHEMBL30299359 | 0.70 | CYP2C9 (0.35) | GAA | |
| SCHEMBL15759227 | 0.70 | HRH1 (0.45) | HRH3SMOHRH1CXCR3 | |
| SCHEMBL30299353 | 0.69 | PNMT (0.43) | — | |
| SCHEMBL30612422 | 0.69 | DRD1 (0.41) | HRH3GAASMN1; SMN2CXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116075303-A | Method of selecting patients treated with a combination of an AXL inhibitor and an immune checkpoint modulator | 卑尔根生物股份公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-115916344-A | AXL inhibitors for antiviral therapy | 卑尔根生物股份公司 | 2023-04-04 | — | — | CN | disclosed |