Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HTR3A | P46098 | 2/20 | 0.51 |
| ▸ | HPGDS | O60760 | 1/20 | 0.51 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.46 |
| ▸ | MET | P08581 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10737787 | 0.86 | HPGDS (0.48) | MEN1KMT2AGLAGAAHTR3A | |
| SCHEMBL28331701 | 0.86 | TERT (0.58) | MEN1KMT2AHPGDSKDM4ESMN1; SMN2 | |
| SCHEMBL15534193 | 0.85 | DRD2 (0.52) | HTR3AHPGDSCHEK1TERT | |
| SCHEMBL15533996 | 0.78 | EGLN2 (0.55) | MEN1KMT2AHPGDSSMN1; SMN2MET | |
| SCHEMBL27971129 | 0.75 | TERT (0.46) | MEN1KMT2AHPGDSKDM4ERAB9A | |
| SCHEMBL28049761 | 0.75 | HTR3A (0.50) | MEN1KMT2AGLAGAAHTR3A | |
| SCHEMBL21835803 | 0.75 | CHEK1 (0.53) | MEN1KMT2AGLAGAAHTR3A | |
| SCHEMBL30326588 | 0.74 | HRH3 (0.57) | HPGDSCHEK1NPC1RAB9AHRH4 | |
| SCHEMBL28089049 | 0.73 | MAPT (0.55) | MEN1KMT2AGAACHEK1KDM4E | |
| SCHEMBL4221803 | 0.73 | MEN1 (0.67) | MEN1KMT2AGLAGAAHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115769077-A | Methods and compositions for treating cancer | 安锦生物科技私人有限公司 | 2023-03-07 | — | — | CN | claimed |