Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 3/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.44 |
| ▸ | IP6K1 | Q92551 | 3/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.41 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.41 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.41 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | C1S | P09871 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28331701 | 0.89 | TERT (0.58) | TERTMAP4K4IP6K1CHRNB2CHRNA4 | |
| SCHEMBL28089049 | 0.86 | MAPT (0.55) | PDE3BPDE3APRKDCMEN1KMT2A | |
| SCHEMBL15534193 | 0.76 | DRD2 (0.52) | TERTCHRNB2CHRNA4EGLN2HPGDS | |
| SCHEMBL8870802 | 0.76 | MAP4K4 (0.54) | TERTMAP4K4PDE3BPDE3AIP6K1 | |
| SCHEMBL10737787 | 0.75 | HPGDS (0.48) | TERTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL30278776 | 0.75 | MEN1 (0.51) | TERTMEN1KMT2ASMN1; SMN2HPGDS | |
| SCHEMBL27389897 | 0.74 | IP6K1 (0.53) | TERTMAP4K4PDE3BPDE3AIP6K1 | |
| SCHEMBL27970978 | 0.73 | MGAM (0.51) | TERTMAP4K4PDE3BPDE3AIP6K1 | |
| SCHEMBL27971212 | 0.71 | MGAM (0.53) | TERTPDE3BPDE3AIP6K1CHRNB2 | |
| SCHEMBL26429922 | 0.71 | ALDH1A1 (0.47) | MEN1KMT2ALMNASMN1; SMN2EGLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103906735-A | Novel aryl-quinoline derivatives | HOFFMANN LA ROCHE | 2014-07-02 | — | — | CN | disclosed |