Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | PLA2G4B | P0C869 | 6/20 | 0.60 |
| ▸ | RARB | P10826 | 3/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.56 |
| ▸ | RELA | Q04206 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL302884 | 0.93 | LMNA (0.63) | TP53TSHRPLA2G4BRARBNFKB1 | |
| SCHEMBL27973869 | 0.89 | LMNA (0.63) | TP53TSHRPLA2G4BRARBNFKB1 | |
| SCHEMBL302600 | 0.86 | LMNA (0.69) | TP53TSHRPLA2G4BNFKB1NFKB2 | |
| SCHEMBL303090 | 0.86 | LMNA (0.69) | TP53TSHRPLA2G4BNFKB1NFKB2 | |
| SCHEMBL13038199 | 0.86 | LMNA (0.69) | TP53TSHRPLA2G4BNFKB1NFKB2 | |
| SCHEMBL14262242 | 0.86 | TP53 (0.82) | TP53TSHRPLA2G4BRARBNFKB1 | |
| SCHEMBL302564 | 0.86 | TP53 (0.82) | TP53TSHRPLA2G4BRARBNFKB1 | |
| SCHEMBL9128354 | 0.86 | TP53 (0.82) | TP53TSHRPLA2G4BRARBNFKB1 | |
| SCHEMBL304398 | 0.86 | TP53 (0.82) | TP53TSHRPLA2G4BRARBNFKB1 | |
| SCHEMBL10524079 | 0.86 | NPC1 (0.72) | TP53TSHRPLA2G4BRARBNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8092712-B2 | Bent-core LC decorated gold nanoclusters | Ridout & Maybee LLP (CA) | 2012-01-10 | — | — | US | disclosed |
| US-20110062385-A1 | BENT-CORE LC DECORATED GOLD NANOCLUSTERS | UNIVERSITY OF MANITOBA (CA) | 2011-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110062385-A1 | BENT-CORE LC DECORATED GOLD NANOCLUSTERS | SLC6A13, SLC6A6, LGALS3 | TP53 3948/4885TSHR 1096/4885PLA2G4B 3812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.