Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.35 |
| ▸ | CAMKK2 | Q96RR4 | 10/20 | 0.33 |
| ▸ | CAMKK1 | Q8N5S9 | 7/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28876061 | 0.94 | MAPT (0.37) | ACMSDCAMKK2CAMKK1MAPTNOTUM | |
| SCHEMBL30280735 | 0.94 | MAPT (0.37) | ACMSDCAMKK2CAMKK1MAPTNOTUM | |
| SCHEMBL30280843 | 0.85 | OPRK1 (0.37) | MAPTPTGDR2DRD2 | |
| SCHEMBL30280884 | 0.80 | CAMKK2 (0.39) | ACMSDCAMKK2CAMKK1MAPTPTGDR2 | |
| SCHEMBL30280981 | 0.78 | PDK2 (0.37) | DRD2 | |
| SCHEMBL30280874 | 0.78 | HSD17B10 (0.37) | CAMKK2CAMKK1PTGDR2DRD2 | |
| SCHEMBL28023583 | 0.76 | GABRP (0.41) | HCAR2 | |
| SCHEMBL12489077 | 0.75 | GABRP (0.36) | ACMSDCAMKK2CAMKK1MAPTPTGDR2 | |
| SCHEMBL30281063 | 0.73 | CAMKK2 (0.35) | CAMKK2CAMKK1HCAR2 | |
| SCHEMBL4392864 | 0.72 | PTGDR2 (0.44) | ACMSDPTGDR2NOTUMABCC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116139138-A | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-110177551-B | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-02-17 | — | — | CN | disclosed |