Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 3/20 | 0.33 |
| ▸ | SRC | P12931 | 3/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25295028 | 0.72 | MAP4K1 (0.37) | SMN1; SMN2ADORA3ADORA2AADORA1ALDH1A1 | |
| SCHEMBL19720097 | 0.70 | L3MBTL1 (0.44) | ADORA3ADORA2AADORA1GAA | |
| SCHEMBL13905270 | 0.65 | ALDH1A1 (0.33) | SMN1; SMN2ALDH1A1TLR7 | |
| SCHEMBL3958356 | 0.65 | ALDH1A1 (0.33) | SMN1; SMN2ALDH1A1TLR7 | |
| SCHEMBL13560302 | 0.64 | ECE1 (0.37) | — | |
| SCHEMBL27425089 | 0.63 | TAS2R38 (0.33) | — | |
| SCHEMBL19198416 | 0.63 | LMNA (0.36) | SMN1; SMN2ALDH1A1GAAHPGD | |
| SCHEMBL28974170 | 0.63 | — | — | |
| SCHEMBL28974164 | 0.63 | — | — | |
| SCHEMBL28974196 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4143195-A1 | IMIDAZOPYRIDAZINES AS MODULATORS OF IL-17 | Janssen Pharmaceutica NV (BE) | 2023-03-08 | — | — | EP | disclosed |