Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27481494 | 0.86 | SHBG (0.40) | MAPK1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL6411255 | 0.83 | NPC1 (0.36) | NPC1RAB9ALMNACASP3SENP8 | |
| SCHEMBL407727 | 0.76 | PKM (0.45) | RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4779069 | 0.73 | MEN1 (0.30) | MAPK1SMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL21191750 | 0.72 | MEN1 (0.43) | NPC1RAB9AMAPK1SMN1; SMN2LMNA | |
| SCHEMBL29770908 | 0.72 | MEN1 (0.43) | NPC1RAB9AMAPK1SMN1; SMN2LMNA | |
| SCHEMBL12186363 | 0.71 | L3MBTL1 (0.47) | NPC1RAB9AMAPK1SMN1; SMN2LMNA | |
| SCHEMBL18174916 | 0.70 | F2RL3 (0.46) | NPC1RAB9AMAPK1SMN1; SMN2LMNA | |
| SCHEMBL13510329 | 0.70 | MAPT (0.50) | NPC1RAB9AMAPK1SMN1; SMN2LMNA | |
| SCHEMBL21511099 | 0.69 | ENPP2 (0.42) | NPC1RAB9AMAPK1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014060405-A2 | AQUEOUS WAX DISPERSIONS AND HAIR STYLING COMPOSITIONS CONTAINING THEM | L'OREAL (FR) | 2014-04-24 | — | — | WO | disclosed |
| US-8404705-B2 | Naphthalene amidine imides | BASF SE (DE) | 2013-03-26 | — | — | US | disclosed |
| US-20100202984-A1 | Naphthalene amidine imides | BASF SE (DE) | 2010-08-12 | — | — | US | disclosed |
| US-7311897-B2 | Triazines which are symmetrically substituted by phenyl, biphenyl, triphenyl or naphthyl can be used as highly effective UV absorbers for cosmetic applications | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100202984-A1 | Naphthalene amidine imides | NES, TXN2, NAT1 | NPC1 1223/4885RAB9A 601/4885MAPK1 2113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.