Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.69 |
| ▸ | PPARD | Q03181 | 4/20 | 0.69 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | KDM1A | O60341 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3026046 | 0.86 | LMNA (0.58) | PPARAPPARDMAPTHDAC1NPC1 | |
| SCHEMBL1553175 | 0.73 | PPARD (0.73) | PPARAPPARDMAPTFFAR1PPARG | |
| SCHEMBL1569198 | 0.73 | LMNA (0.60) | PPARAPPARDMAPTHDAC1NPC1 | |
| SCHEMBL3029995 | 0.73 | HDAC8 (0.56) | KDM1AHDAC1ALDH1A1GAA | |
| SCHEMBL5023897 | 0.72 | PPARD (0.75) | PPARAPPARDMAPTFFAR1PPARG | |
| SCHEMBL3033902 | 0.72 | MLYCD (0.69) | HDAC1GAA | |
| SCHEMBL1553162 | 0.71 | ALDH1A1 (0.62) | PPARAPPARDMAPTFFAR1PPARG | |
| SCHEMBL1553892 | 0.71 | PPARD (0.73) | PPARAPPARDFFAR1PPARG | |
| SCHEMBL1508353 | 0.71 | NPC1 (0.58) | PPARAPPARDMAPTFFAR1PPARG | |
| SCHEMBL6572354 | 0.71 | HDAC6 (0.72) | PPARAKDM1AHDAC1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216796-A1 | N-HYDROXY-NAPHTHALENE DICARBOXAMIDE AND N-HYDROXY-BIPHENYL-DICARBOXAMIDE COMPOUNDS AS HISTONE DEACETYLASE INHIBITORS | KATTAR SOLOMON | 2010-08-26 | — | — | US | claimed |
| US-20100216796-A1 | N-HYDROXY-NAPHTHALENE DICARBOXAMIDE AND N-HYDROXY-BIPHENYL-DICARBOXAMIDE COMPOUNDS AS HISTONE DEACETYLASE INHIBITORS | KATTAR SOLOMON | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216796-A1 | N-HYDROXY-NAPHTHALENE DICARBOXAMIDE AND N-HYDROXY-BIPHENYL-DICARBOXAMIDE COMPOUNDS AS HISTONE DEACETYLASE INHIBITORS | BRDT, AADAC, ACIN1 | PPARA 692/4885PPARD 1396/4885MAPT 974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.