Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 7/20 | 0.39 |
| ▸ | ATIC | P31939 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 5/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | SGK1 | O00141 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20354886 | 1.00 | ACLY (0.39) | ACLYATICSLC22A12CYP2C9SGK1 | |
| SCHEMBL20355215 | 0.89 | ALDH1A1 (0.39) | ACLYSLC22A12SCN5A | |
| SCHEMBL30286617 | 0.89 | ALDH1A1 (0.39) | ACLYSLC22A12SCN5A | |
| SCHEMBL30286518 | 0.88 | ACLY (0.42) | ACLYCYP2C9SGK1CCR2 | |
| SCHEMBL20354889 | 0.88 | ACLY (0.42) | ACLYCYP2C9SGK1CCR2 | |
| SCHEMBL30286645 | 0.85 | ACLY (0.39) | ACLYCYP2C9SGK1CYP3A4CCR2 | |
| SCHEMBL20340319 | 0.85 | ACLY (0.39) | ACLYCYP2C9SGK1CYP3A4CCR2 | |
| SCHEMBL20355286 | 0.85 | ATIC (0.42) | ACLYATICSLC22A12CYP2C9SGK1 | |
| SCHEMBL30286411 | 0.85 | ATIC (0.42) | ACLYATICSLC22A12CYP2C9SGK1 | |
| SCHEMBL20355214 | 0.84 | HSD11B1 (0.38) | ACLYCYP2C9SGK1CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | claimed |
| CN-116283712-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116036078-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | disclosed |