Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | HTR1D | P28221 | 1/20 | 0.49 |
| ▸ | HTR1B | P28222 | 1/20 | 0.49 |
| ▸ | HTR1E | P28566 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30288466 | 1.00 | SLC6A2 (0.49) | SLC6A2SLC6A3SLC6A4HTR2AHTR2C | |
| SCHEMBL15281774 | 0.81 | MAPT (0.57) | SLC6A2SLC6A3SLC6A4HTR2AHTR2C | |
| SCHEMBL15281761 | 0.81 | MAPT (0.57) | SLC6A2SLC6A3SLC6A4HTR2AHTR2C | |
| SCHEMBL30288451 | 0.81 | CHRNB2 (0.46) | HTR6CHRNB2CHRNA7CHRNA4TAAR1 | |
| SCHEMBL30288464 | 0.81 | MAPT (0.45) | HTR2AHTR2CHTR2BHTR6CHRNB2 | |
| SCHEMBL30288449 | 0.81 | MAPT (0.45) | HTR2AHTR2CHTR2BHTR6CHRNB2 | |
| SCHEMBL30288454 | 0.81 | CHRNB2 (0.46) | HTR6CHRNB2CHRNA7CHRNA4TAAR1 | |
| SCHEMBL30288457 | 0.80 | SLC6A2 (0.49) | SLC6A2SLC6A3SLC6A4HTR2AHTR2C | |
| SCHEMBL30288456 | 0.80 | SLC6A2 (0.49) | SLC6A2SLC6A3SLC6A4HTR2AHTR2C | |
| SCHEMBL31599467 | 0.78 | KDM4E (0.54) | MAPTNR4A2ALDH1A1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4146198-A1 | NOVEL COMPOSITIONS OF MATTER AND PHARMACEUTICAL COMPOSITIONS | Psilera Inc. (US) | 2023-03-15 | — | — | EP | claimed |
| US-20260124174-A1 | COMPOSITIONS OF MATTER AND PHARMACEUTICAL COMPOSITIONS | ATAI THERAPEUTICS INC (US) | 2026-05-07 | — | — | US | disclosed |
| US-20260115168-A1 | COMPOSITIONS OF MATTER AND PHARMACEUTICAL COMPOSITIONS | ATAI THERAPEUTICS INC (US) | 2026-04-30 | — | — | US | disclosed |
| US-20260115167-A1 | NOVEL COMPOSITIONS OF MATTER AND PHARMACEUTICAL COMPOSITIONS | ATAI THERAPEUTICS INC (US) | 2026-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260115168-A1 | COMPOSITIONS OF MATTER AND PHARMACEUTICAL COMPOSITIONS | PNMT, HTR5A, TPH2 | SLC6A2 17/4885SLC6A3 25/4885SLC6A4 4/4885 |
| US-20260115167-A1 | NOVEL COMPOSITIONS OF MATTER AND PHARMACEUTICAL COMPOSITIONS | HTR2C, HTR5A, TPH2 | SLC6A2 8/4885SLC6A3 25/4885SLC6A4 7/4885 |
| US-20260124174-A1 | COMPOSITIONS OF MATTER AND PHARMACEUTICAL COMPOSITIONS | MAOB, TPH1, TPH2 | SLC6A2 7/4885SLC6A3 16/4885SLC6A4 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.