Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.38 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20765376 | 1.00 | MAPT (0.55) | MAPTESR1ALDH1A1HTTLMNA | |
| SCHEMBL19145383 | 0.81 | L3MBTL1 (0.44) | MAPTALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL847830 | 0.81 | KMT2A (0.50) | MAPTESR1ALDH1A1HDAC4HDAC6 | |
| SCHEMBL14478168 | 0.81 | KIF11 (0.50) | MAPTESR1HTTLMNASMN1; SMN2 | |
| SCHEMBL28450717 | 0.80 | KIF11 (0.41) | MAPTESR1HTTLMNASMN1; SMN2 | |
| SCHEMBL29913597 | 0.79 | KIF11 (0.51) | KIF11 | |
| SCHEMBL1541448 | 0.79 | KIF11 (0.51) | KIF11 | |
| SCHEMBL19117614 | 0.78 | RORC (0.44) | MAPTALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL8490622 | 0.78 | LMNA (0.48) | HTTLMNASMN1; SMN2TRPV4KDM4E | |
| SCHEMBL1459011 | 0.78 | TRPV4 (0.42) | MAPTESR1ALDH1A1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116462674-A | Morpholinyl pyridone compounds | 思普瑞特生物科学公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-116444510-A | Morpholinyl pyridone compounds | 思普瑞特生物科学公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-111108102-B | Morpholinyl pyridone compounds | 思普瑞特生物科学公司 | 2023-04-28 | — | — | CN | disclosed |