Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.37 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | PYGL | P06737 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22208718 | 0.84 | CFTR (0.45) | ALDH1A1GAAHSD17B10CYP1A2CYP2C9 | |
| SCHEMBL22208588 | 0.83 | TDP1 (0.47) | ALDH1A1GAAPOLBHSD17B10CYP2C19 | |
| SCHEMBL5500439 | 0.81 | NNMT (0.41) | MAPK10PDE4BPOLBCYP1A2CYP2C9 | |
| SCHEMBL18530548 | 0.80 | PLK1 (0.49) | PLK1ALDH1A1GAAHSD17B10AKR1B10 | |
| SCHEMBL8573287 | 0.78 | PLK1 (0.57) | PLK1ALDH1A1PDE4DGAAPOLB | |
| SCHEMBL8566810 | 0.76 | GAA (0.47) | PLK1ALDH1A1NOTUMGAAPOLB | |
| Acetic Acid Methyl Ester SCHEMBL9750460 | 0.74 | PLK1 (0.57) | PLK1ALDH1A1MAPK9MAPK10GAA | |
| SCHEMBL5196436 | 0.74 | NPC1 (0.56) | PLK1ALDH1A1HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL15621232 | 0.73 | PLK1 (0.55) | PLK1ALDH1A1GAAPOLBHSD17B10 | |
| SCHEMBL5954008 | 0.72 | PLK1 (0.54) | PLK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115785088-A | Compounds as SOS1 inhibitors and uses thereof | 南京圣和药业股份有限公司 | 2023-03-14 | — | — | CN | disclosed |