Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 1/20 | 0.65 |
| ▸ | PARP1 | P09874 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CMA1 | P23946 | 1/20 | 0.51 |
| ▸ | AHR | P35869 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30015279 | 1.00 | MMP12 (0.65) | MMP12PARP1MAPTALDH1A1KMT2A | |
| SCHEMBL5987554 | 0.98 | MMP12 (0.63) | MMP12PARP1MAPTALDH1A1KMT2A | |
| SCHEMBL304249 | 0.86 | DRD4 (0.56) | MMP12PARP1MAPTALDH1A1KMT2A | |
| SCHEMBL15964651 | 0.83 | AHR (0.49) | MMP12PARP1MAPTDRD4CMA1 | |
| SCHEMBL8490860 | 0.80 | MMP12 (0.41) | MMP12PARP1MAPTALDH1A1KMT2A | |
| SCHEMBL6321386 | 0.80 | NR3C2 (0.58) | MMP12PARP1MAPTALDH1A1KMT2A | |
| SCHEMBL279594 | 0.79 | MMP12 (1.00) | MMP12PARP1MAPTALDH1A1KMT2A | |
| SCHEMBL861110 | 0.79 | MMP12 (0.65) | MMP12PARP1MAPTALDH1A1KMT2A | |
| SCHEMBL277585 | 0.79 | MMP12 (0.65) | MMP12PARP1MAPTALDH1A1KMT2A | |
| SCHEMBL707058 | 0.79 | MMP12 (0.65) | MMP12PARP1ALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084815-A | Synthesis method of 7-bromo-6-chloro-3, 4-dihydro-2H-1, 4-benzoxazine | 南通大学 | 2024-05-28 | — | — | CN | claimed |
| WO-2025099111-A1 | NEW TELESCOPING SYNTHESES OF 6-HYDROXY-BENZOMORPHOLINE (3,4-DIHYDRO-2H-1,4-BENZOXAZIN-6-OL) | WELLA GERMANY GMBH (DE) | 2025-05-15 | — | — | WO | disclosed |
| CN-118084815-A | Synthesis method of 7-bromo-6-chloro-3, 4-dihydro-2H-1, 4-benzoxazine | 南通大学 | 2024-05-28 | — | — | CN | disclosed |
| CN-110092782-B | Benzo-hexaazacyclo compound and preparation method and application thereof | 中国科学院广州生物医药与健康研究院 | 2022-10-21 | — | — | CN | disclosed |
| US-20210380570-A1 | KRAS G12C INHIBITORS | Mirati Therapeutics, Inc. | 2021-12-09 | — | — | US | disclosed |
| EP-3790551-A1 | KRAS G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2021-03-17 | — | — | EP | disclosed |
| US-10851215-B2 | Graphene-augmented composite materials | THE BOEING COMPANY (US) | 2020-12-01 | — | — | US | disclosed |
| WO-2019217307-A1 | KRAS G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2019-11-14 | — | — | WO | disclosed |
| WO-2019217307-A1 | KRAS G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2019-11-14 | — | — | WO | disclosed |
| US-20190338087-A1 | GRAPHENE-AUGMENTED COMPOSITE MATERIALS | THE BOEING COMPANY (US) | 2019-11-07 | — | — | US | disclosed |
| US-20060173183-A1 | Multicyclic bis-amide MMP inhibitors | ALANTOS PHARMACEUTICALS, INC., | 2006-08-03 | — | — | US | disclosed |
| EP-1660431-A2 | PHENOXYACETIC ACID DERIVATIVES | Astrazeneca AB (SE) | 2006-05-31 | — | — | EP | disclosed |
| US-20050222148-A1 | Phenylaminopropanol derivatives and methods of their use | WYETH (US) | 2005-10-06 | — | — | US | disclosed |
| US-20050222142-A1 | Phenylaminopropanol derivatives and methods of their use | WYETH (US) | 2005-10-06 | — | — | US | disclosed |
| WO-2005018529-A2 | PHENOXIACETIC ACID DERIVATIVES | ASTRAZENECA AB (SE) | 2005-03-03 | — | — | WO | disclosed |
| EP-0769495-B1 | Fungicides | ZENECA LTD (GB) | 1999-04-21 | — | — | EP | disclosed |
| US-5830890-A | NITROGEN HETEROCYCLE ATTACHED THROUGH OXYMETHYLENE GROUP TO PHENYL RING WITH O-METHYL 3-METHOXYACRYLATE OR WITH METHYL 3-METHOXYIMINOACETATE OR AMIDE DERIVATIVE | ZENECA LIMITED (GB) | 1998-11-03 | — | — | US | disclosed |
| EP-0858997-A1 | Fungicides | ZENECA LIMITED (GB) | 1998-08-19 | — | — | EP | disclosed |
| EP-0769495-A1 | Fungicides | ZENECA LIMITED (GB) | 1997-04-23 | — | — | EP | disclosed |
| US-3935203-A | ANALGESICS, ANTI-OEDEMATOUS | CERPHA (FR) | 1976-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222148-A1 | Phenylaminopropanol derivatives and methods of their use | PAH, PNMT, COMT | MMP12 2805/4885PARP1 1187/4885MAPT 2326/4885 |
| US-20210380570-A1 | KRAS G12C INHIBITORS | KRAS, NRAS, HRAS | MMP12 1433/4885PARP1 1128/4885MAPT 3928/4885 |
| US-20060173183-A1 | Multicyclic bis-amide MMP inhibitors | MMP13, MMP3, MMP11 | MMP12 7/4885PARP1 190/4885MAPT 2159/4885 |
| US-20050222142-A1 | Phenylaminopropanol derivatives and methods of their use | PAH, PNMT, COMT | MMP12 2805/4885PARP1 1187/4885MAPT 2326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.