Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | PRF1 | P14222 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PTPRC | P08575 | 1/20 | 0.47 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11249792 | 0.88 | MAPT (0.53) | MAPTHSD17B10GAACYP3A4ALDH1A1 | |
| SCHEMBL7695944 | 0.84 | MAPT (0.50) | MAPTHSD17B10PRF1LMNAGAA | |
| SCHEMBL7780577 | 0.84 | PRF1 (0.51) | MAPTHSD17B10PRF1LMNAGAA | |
| SCHEMBL7781294 | 0.84 | MAPT (0.49) | MAPTHSD17B10PRF1LMNAGAA | |
| SCHEMBL3039890 | 0.84 | PRF1 (0.70) | MAPTHSD17B10PRF1LMNAGAA | |
| SCHEMBL751196 | 0.82 | KDM4E (0.57) | MAPTHSD17B10GAAKDM4EALDH1A1 | |
| SCHEMBL1917980 | 0.82 | ALDH1A1 (0.54) | MAPTHSD17B10GAANPC1KDM4E | |
| SCHEMBL1466724 | 0.82 | MAPT (0.58) | MAPTHSD17B10PRF1LMNAGAA | |
| Hydrochloric Acid SCHEMBL18149161 | 0.82 | MAPT (0.50) | MAPTHSD17B10PRF1LMNAGAA | |
| SCHEMBL7636169 | 0.81 | PRF1 (0.68) | MAPTHSD17B10PRF1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3356338-B1 | METHODS FOR SYNTHESIZING RHODAMINE DYES | PROMEGA CORP (US) | 2020-06-17 | — | — | EP | disclosed |
| EP-3356338-A1 | METHODS FOR SYNTHESIZING RHODAMINE DYES | Promega Corporation (US) | 2018-08-08 | — | — | EP | disclosed |
| US-20170096560-A1 | METHODS FOR SYNTHESIZING RHODAMINE DYES | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2017-04-06 | — | — | US | disclosed |
| US-7687645-B2 | Intermediates for the preparation of citalopram and escitalopram | H. LUNDBECK A/S (DK) | 2010-03-30 | — | — | US | disclosed |
| US-20080058536-A1 | Intermediates for the preparation of citalopram and escitalopram | H. LUNDBECK A/S (DK) | 2008-03-06 | — | — | US | disclosed |
| EP-1611118-A2 | INTERMEDIATES FOR THE PREPARATION OF CITALOPRAM AND ESCITALOPRAM | H. LUNDBECK A/S (DK) | 2006-01-04 | — | — | EP | disclosed |
| WO-2004083197-A2 | INTERMEDIATES FOR THE PREPARATION OF CITALOPRAM AND ESCITALOPRAM | H. LUNDBECK A/S (DK) | 2004-09-30 | — | — | WO | disclosed |
| EP-0911320-B1 | 1,2-Di-substituted benzenecarboxamide derivative, hair growth promoter and external composition for skin using the same | SHISEIDO CO LTD (JP) | 2002-07-24 | — | — | EP | disclosed |
| US-6114325-A | 1,2-di-substituted benzene-carboxamide derivative, hair growth promoter and external composition for skin using the same | SHISEIDO CO., LTD. (JP) | 2000-09-05 | — | — | US | disclosed |
| CN-1224712-A | 1,2-Di-substituted benzene-carboxamide derivative, hair growth promoter and external composition for skin using the same | SHISEIDO CO LTD (JP) | 1999-08-04 | — | — | CN | disclosed |
| EP-0911320-A2 | 1,2-Di-substituted benzenecarboxamide derivative, hair growth promoter and external composition for skin using the same | SHISEIDO COMPANY LIMITED (JP) | 1999-04-28 | — | — | EP | disclosed |
| US-4041173-A | ANTI-ASTHMATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1977-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058536-A1 | Intermediates for the preparation of citalopram and escitalopram | SLC6A4, HTR4, HTR3C | MAPT 177/4885HSD17B10 63/4885PRF1 4861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.