Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRF1 | P14222 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 6/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.50 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3039890 | 0.87 | PRF1 (0.70) | PRF1ALDH1A1ESR1LMNAMAPK1 | |
| SCHEMBL19770242 | 0.86 | PRF1 (0.47) | PRF1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL11246590 | 0.85 | MAPT (0.53) | PRF1ALDH1A1MEN1KMT2AESR1 | |
| SCHEMBL11242897 | 0.85 | MAPT (0.53) | PRF1ALDH1A1MEN1KMT2AESR1 | |
| SCHEMBL20107457 | 0.81 | PRF1 (0.50) | PRF1ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL3029409 | 0.79 | MAPT (0.55) | PRF1ALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL2653935 | 0.79 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2AESR1TSHR | |
| SCHEMBL38659727 | 0.79 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2AESR1TSHR | |
| SCHEMBL8466946 | 0.79 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2AESR1TSHR | |
| SCHEMBL31634617 | 0.79 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2AESR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687645-B2 | Intermediates for the preparation of citalopram and escitalopram | H. LUNDBECK A/S (DK) | 2010-03-30 | — | — | US | disclosed |
| US-20080058536-A1 | Intermediates for the preparation of citalopram and escitalopram | H. LUNDBECK A/S (DK) | 2008-03-06 | — | — | US | disclosed |
| EP-1611118-A2 | INTERMEDIATES FOR THE PREPARATION OF CITALOPRAM AND ESCITALOPRAM | H. LUNDBECK A/S (DK) | 2006-01-04 | — | — | EP | disclosed |
| WO-2004083197-A2 | INTERMEDIATES FOR THE PREPARATION OF CITALOPRAM AND ESCITALOPRAM | H. LUNDBECK A/S (DK) | 2004-09-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058536-A1 | Intermediates for the preparation of citalopram and escitalopram | SLC6A4, HTR4, HTR3C | PRF1 4861/4885ALDH1A1 488/4885MEN1 2717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.