SCHEMBL302970

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2187930	0.81	LMNA (0.48)	LMNAGAAALDH1A1MEN1HPGD
	SCHEMBL302225	0.81	LMNA (0.60)	LMNAGAAALDH1A1MEN1KMT2A
	SCHEMBL302098	0.81	KEAP1 (0.49)	LMNAALDH1A1MEN1HPGDKMT2A
	SCHEMBL3378121	0.80	MAPT (0.46)	LMNAALDH1A1MEN1KMT2AMAPT
	SCHEMBL3376926	0.79	MAPT (0.60)	LMNAGAAALDH1A1MEN1KMT2A
	SCHEMBL2189508	0.78	HTT (0.70)	LMNAGAAMEN1KMT2AMAPT
	SCHEMBL3380011	0.78	DAGLA (0.55)	LMNAALDH1A1MAPT
	SCHEMBL3379839	0.78	LMNA (0.56)	LMNAALDH1A1MEN1KMT2AMAPT
	SCHEMBL3376229	0.78	ALDH1A1 (0.53)	LMNAGAAALDH1A1HPGDMAPT
	SCHEMBL3237944	0.77	TP53 (0.74)	LMNAGAAALDH1A1MEN1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.