Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | CCR2 | P41597 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MIF | P14174 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | APLNR | P35414 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL160878 | 1.00 | ALDH1A1 (0.52) | ALDH1A1CYP3A4HPGDABCB11NR3C1 | |
| Pentachlorophenol SCHEMBL10685234 | 0.84 | ALDH1A1 (0.40) | ALDH1A1CYP3A4HPGDABCB11NR3C1 | |
| SCHEMBL2768046 | 0.82 | ALDH1A1 (0.48) | ALDH1A1CYP3A4HPGDABCB11NR3C1 | |
| SCHEMBL207554 | 0.82 | ALDH1A1 (0.62) | ALDH1A1CYP3A4HPGDABCB11NR3C1 | |
| SCHEMBL29374052 | 0.82 | ALDH1A1 (0.62) | ALDH1A1CYP3A4HPGDABCB11NR3C1 | |
| SCHEMBL8675112 | 0.80 | ACHE (0.37) | ALDH1A1CYP3A4HPGDABCB11NR3C1 | |
| SCHEMBL2769195 | 0.79 | ALDH1A1 (0.46) | ALDH1A1CYP3A4HPGDABCB11NR3C1 | |
| SCHEMBL7256052 | 0.79 | ALDH1A1 (0.46) | ALDH1A1CYP3A4HPGDABCB11NR3C1 | |
| SCHEMBL2770263 | 0.79 | ALDH1A1 (0.46) | ALDH1A1CYP3A4HPGDABCB11NR3C1 | |
| SCHEMBL93162 | 0.76 | CYP3A4 (0.52) | ALDH1A1CYP3A4HPGDALOX15TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119080660-A | Thiosemicarbazide menthyl formate compound, preparation method and application thereof | 南京林业大学 | 2024-12-06 | — | — | CN | claimed |
| EP-4139286-B1 | SUBSTITUTED AMINOTHIAZOLES AS DGKZETA INHIBITORS FOR IMMUNE ACTIVATION | BAYER AG (DE) | 2025-02-26 | — | — | EP | disclosed |
| CN-119080660-A | Thiosemicarbazide menthyl formate compound, preparation method and application thereof | 南京林业大学 | 2024-12-06 | — | — | CN | disclosed |
| US-11964953-B2 | Substituted aminothiazoles as DGKzeta inhibitors for immune activation | BAYER AKTIENGESELLSCHAFT (DE) | 2024-04-23 | — | — | US | disclosed |
| US-20230167078-A1 | SUBSTITUTED AMINOTHIAZOLES AS DGKZETA INHIBITORS FOR IMMUNE ACTIVATION | BAYER AKTIENGESELLSCHAFT (DE) | 2023-06-01 | — | — | US | disclosed |
| US-20230139936-A1 | SUBSTITUTED AMINOTHIAZOLES AS DGKZETA INHIBITORS FOR IMMUNE ACTIVATION | BAYER AKTIENGESELLSCHAFT (DE) | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230139936-A1 | SUBSTITUTED AMINOTHIAZOLES AS DGKZETA INHIBITORS FOR IMMUNE ACTIVATION | DGKZ, DGKA, DGKG | ALDH1A1 3985/4885CYP3A4 3897/4885HPGD 2344/4885 |
| US-20230167078-A1 | SUBSTITUTED AMINOTHIAZOLES AS DGKZETA INHIBITORS FOR IMMUNE ACTIVATION | DGKZ, DGKA, DGKG | ALDH1A1 3985/4885CYP3A4 3897/4885HPGD 2344/4885 |
| US-11964953-B2 | Substituted aminothiazoles as DGKzeta inhibitors for immune activation | DGKZ, DGKA, DGKG | ALDH1A1 3985/4885CYP3A4 3897/4885HPGD 2344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.