SCHEMBL30301415

SCHEMBL30301415

NC(=O)c1cc2cc(O)ccc2n1CCN1CCC(Cc2ccccc2)CC1

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.48
GRIN2A Q12879 4/20 0.47
GRIN2B Q13224 4/20 0.47
GRIN2D O15399 3/20 0.47
GRIN3B O60391 3/20 0.47
GRIN1 Q05586 3/20 0.47
GRIN2C Q14957 3/20 0.47
GRIN3A Q8TCU5 3/20 0.47
ADRA1D P25100 2/20 0.47
ADRA1A P35348 2/20 0.47
ADRA1B P35368 2/20 0.47
PRMT3 O60678 1/20 0.47
CARM1 Q86X55 1/20 0.47
PRMT6 Q96LA8 1/20 0.47
PRMT1 Q99873 1/20 0.47
PRMT8 Q9NR22 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30388922 0.90 GAA (0.56) GAAGRIN2BPRMT3CARM1PRMT6
SCHEMBL30389462 0.89 GAA (0.52) GAAPRMT3CARM1PRMT6PRMT1
SCHEMBL30786610 0.89 CCR3 (0.48) GAAPRMT3CARM1PRMT6PRMT1
SCHEMBL27008237 0.74 GAA (0.51) GAAPRMT3CARM1PRMT6PRMT1
SCHEMBL3867284 0.71 PRMT3 (0.66) GAAPRMT3CARM1PRMT6PRMT1
SCHEMBL7078849 0.70 GAA (0.49) GAA
SCHEMBL7402560 0.70 SLC6A2 (0.73)
SCHEMBL5888792 0.69 HTR7 (0.68) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL7532115 0.69 GRIN2B (0.62) GRIN2B
SCHEMBL7407241 0.69 CCR3 (0.82) GRIN2AGRIN2BGRIN2DGRIN3BGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240018119-A1 CARBOXAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS TRINEURO (KR) 2024-01-18 US disclosed
CN-116057049-A Carboxamide derivatives and pharmaceutical composition for preventing or treating mental diseases containing the same as active ingredient 大邱庆北尖端医疗产业振兴财团 2023-05-02 CN disclosed
EP-4159725-A1 CARBOXAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS Daegu-Gyeongbuk Medical Innovation Foundation (KR) 2023-04-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240018119-A1 CARBOXAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS MAOA, DRD2, MAOB GAA 1486/4885GRIN2A 97/4885GRIN2B 242/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.