Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1274727 | 0.94 | CA1 (0.41) | — | |
| SCHEMBL11547358 | 0.94 | CA1 (0.41) | — | |
| SCHEMBL11500943 | 0.94 | CA1 (0.41) | — | |
| SCHEMBL7716512 | 0.94 | CA1 (0.41) | — | |
| SCHEMBL7631487 | 0.94 | CA1 (0.41) | — | |
| SCHEMBL8055981 | 0.94 | CA1 (0.41) | — | |
| SCHEMBL208042 | 0.94 | CA1 (0.41) | — | |
| SCHEMBL8959411 | 0.94 | CA1 (0.41) | — | |
| SCHEMBL19327192 | 0.94 | CA1 (0.41) | — | |
| Silver SCHEMBL527467 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2012500848-A | — | — | 2012-01-12 | — | — | JP | claimed |
| US-8044214-B2 | Process for preparing isoxazole compounds | ANGUS CHEMICAL COMPANY (US) | 2011-10-25 | — | — | US | claimed |
| EP-2318381-A1 | PROCESS FOR PREPARING ISOXAZOLE COMPOUNDS | Dow Global Technologies LLC (US) | 2011-05-11 | — | — | EP | claimed |
| WO-2010025035-A1 | PROCESS FOR PREPARING ISOXAZOLE COMPOUNDS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-03-04 | — | — | WO | claimed |
| US-20100048910-A1 | PROCESS FOR PREPARING ISOXAZOLE COMPOUNDS | ANGUS CHEMICAL COMPANY | 2010-02-25 | — | — | US | claimed |
| EP-2599840-B1 | SILVER INK COMPOSITION AND BASE MATERIAL | TOPPAN FORMS CO LTD (JP) | 2018-07-25 | — | — | EP | disclosed |
| US-9328254-B2 | Silver ink composition and substrate | TOPPAN FORMS CO., LTD. (JP) | 2016-05-03 | — | — | US | disclosed |
| EP-2599840-A1 | SILVER INK COMPOSITION AND BASE MATERIAL | Toppan Forms Co., Ltd. (JP) | 2013-06-05 | — | — | EP | disclosed |
| US-20130121872-A1 | Silver Ink Composition and Substrate | TOPPAN FORMS CO., LTD. (JP) | 2013-05-16 | — | — | US | disclosed |
| US-8044214-B2 | Process for preparing isoxazole compounds | ANGUS CHEMICAL COMPANY (US) | 2011-10-25 | — | — | US | disclosed |
| EP-2318381-A1 | PROCESS FOR PREPARING ISOXAZOLE COMPOUNDS | Dow Global Technologies LLC (US) | 2011-05-11 | — | — | EP | disclosed |
| WO-2010025035-A1 | PROCESS FOR PREPARING ISOXAZOLE COMPOUNDS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-03-04 | — | — | WO | disclosed |
| US-20100048910-A1 | PROCESS FOR PREPARING ISOXAZOLE COMPOUNDS | ANGUS CHEMICAL COMPANY | 2010-02-25 | — | — | US | disclosed |