SCHEMBL30307673

SCHEMBL30307673

Cc1cc(CC=O)nc(C)n1

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 1/20 0.41
LMNA P02545 1/20 0.34
ALDH1A1 P00352 2/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
HSD17B10 Q99714 1/20 0.32
HTT P42858 1/20 0.31
MEN1 O00255 1/20 0.30
HPGD P15428 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL875422 0.79 NOS2 (0.40) LMNA
SCHEMBL5897867 0.76 SLC6A3 (0.45) SLC6A3LMNAALDH1A1NPC1RAB9A
SCHEMBL10225997 0.75 NPC1 (0.34) LMNAALDH1A1NPC1RAB9AHTT
SCHEMBL805465 0.73 NOS3 (0.45) SLC6A3LMNAALDH1A1NPC1RAB9A
SCHEMBL6505673 0.73 LMNA (0.39) LMNAALDH1A1HTTKMT2A
SCHEMBL4915807 0.71 SLC6A3 (0.41) SLC6A3LMNAALDH1A1NPC1RAB9A
SCHEMBL5897870 0.71 SLC6A3 (0.41) SLC6A3LMNAALDH1A1NPC1RAB9A
SCHEMBL874707 0.71 HTT (0.47) LMNAALDH1A1HSD17B10HTTKMT2A
Hydrochloric Acid SCHEMBL4918186 0.70 SLC6A3 (0.40) SLC6A3LMNAALDH1A1NPC1RAB9A
SCHEMBL13026558 0.70 NOS2 (0.48) SLC6A3ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115551841-A Azetidin-3-ylcarbinol derivatives as modulators of the CCR6 receptor 爱杜西亚药品有限公司 2022-12-30 CN disclosed