Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6505673 | 0.78 | LMNA (0.39) | HTTLMNAPOLBAPOBEC3GMAPT | |
| SCHEMBL30307673 | 0.71 | SLC6A3 (0.41) | HTTLMNAALDH1A1KMT2AHSD17B10 | |
| SCHEMBL875422 | 0.71 | NOS2 (0.40) | LMNA | |
| SCHEMBL5092348 | 0.71 | LMNA (0.44) | HTTLMNATSHRMAPTGAA | |
| SCHEMBL6118354 | 0.70 | ALDH1A1 (0.33) | LMNAPOLBTSHRMAPTALDH1A1 | |
| SCHEMBL21326170 | 0.70 | HTT (0.39) | HTTLMNAPOLBALDH1A1CYP3A4 | |
| SCHEMBL2937637 | 0.69 | HTT (0.48) | HTTLMNAPOLBAPOBEC3GTSHR | |
| SCHEMBL15058380 | 0.69 | ALDH1A1 (0.36) | LMNAMAPTGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL10225997 | 0.67 | NPC1 (0.34) | HTTLMNAPOLBTSHRMAPT | |
| SCHEMBL11981610 | 0.67 | HTT (0.52) | HTTLMNAPOLBAPOBEC3GTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2638011-A1 | NOVEL MICROBIOCIDES | Syngenta Participations AG (CH) | 2013-09-18 | — | — | EP | disclosed |
| EP-2619181-A1 | NOVEL MICROBIOCIDES | Syngenta Participations AG (CH) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012062844-A1 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-05-18 | — | — | WO | disclosed |
| WO-2012038521-A1 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-03-29 | — | — | WO | disclosed |
| EP-0623125-A1 | BRIDGED HETEROCYCLIC FUNGICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-11-09 | — | — | EP | disclosed |