Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5R1 | Q15078 | 10/20 | 1.00 |
| ▸ | CCNE1 | P24864 | 9/20 | 1.00 |
| ▸ | CDK2 | P24941 | 9/20 | 1.00 |
| ▸ | CDK5 | Q00535 | 9/20 | 1.00 |
| ▸ | FLT3 | P36888 | 5/20 | 1.00 |
| ▸ | CDK1 | P06493 | 8/20 | 0.81 |
| ▸ | CCNB1 | P14635 | 7/20 | 0.81 |
| ▸ | AURKA | O14965 | 2/20 | 0.81 |
| ▸ | IKBKB | O14920 | 1/20 | 0.81 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.81 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.76 |
| ▸ | CDK9 | P50750 | 2/20 | 0.76 |
| ▸ | STK17B | O94768 | 3/20 | 0.73 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.73 |
| ▸ | GSK3B | P49841 | 7/20 | 0.69 |
| ▸ | GSK3A | P49840 | 5/20 | 0.69 |
| ▸ | CCNB2 | O95067 | 4/20 | 0.69 |
| ▸ | CCNB3 | Q8WWL7 | 4/20 | 0.69 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.67 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29904409 | 0.89 | CCNE1 (1.00) | CDK5R1CCNE1CDK2CDK5FLT3 | |
| Indirubin-3-Monoxime SCHEMBL29354191 | 0.82 | CDK5R1 (1.00) | CDK5R1CCNE1CDK2CDK5FLT3 | |
| SCHEMBL29484209 | 0.80 | GSK3B (1.00) | CDK5R1CCNE1CDK2CDK5FLT3 | |
| SCHEMBL30319818 | 0.80 | GSK3B (0.83) | CDK5R1CCNE1CDK2CDK5FLT3 | |
| SCHEMBL30319828 | 0.80 | CDK5R1 (1.00) | CDK5R1CCNE1CDK2CDK5FLT3 | |
| SCHEMBL30141665 | 0.80 | CDK5R1 (1.00) | CDK5R1CCNE1CDK2CDK5FLT3 | |
| SCHEMBL30319823 | 0.77 | CCNE1 (0.63) | CDK5R1CCNE1CDK2CDK5FLT3 | |
| SCHEMBL151534 | 0.73 | CTSV (0.79) | CDK5R1CCNE1CDK2CDK5FLT3 | |
| SCHEMBL30272743 | 0.73 | CTSV (0.79) | CDK5R1CCNE1CDK2CDK5FLT3 | |
| SCHEMBL30272741 | 0.73 | CTSV (0.79) | CDK5R1CCNE1CDK2CDK5FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3866786-B1 | COMPOSITIONS AND METHODS FOR SUPPRESSING AND/OR TREATING METABOLIC DISEASES AND/OR A CLINICAL CONDITION THEREOF | CK REGEON INC (KR) | 2024-09-18 | — | — | EP | disclosed |
| CN-112334131-B | Pharmaceutical composition comprising indirubin derivative as active ingredient | CK生物技术公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-111093620-B | Composition for preventing hair loss or promoting hair growth | CK雷容股份有限公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-115969814-A | Novel pharmaceutical formulations containing indirubin and derivatives thereof and methods of making and using the same | 法斯瑞斯公司 | 2023-04-18 | — | — | CN | disclosed |
| CN-110536686-B | Pharmaceutical composition comprising indirubin derivative as active ingredient | CK雷容股份有限公司 | 2023-03-24 | — | — | CN | disclosed |