Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5R1 | Q15078 | 16/20 | 1.00 |
| ▸ | GSK3B | P49841 | 15/20 | 1.00 |
| ▸ | CDK5 | Q00535 | 15/20 | 1.00 |
| ▸ | GSK3A | P49840 | 12/20 | 1.00 |
| ▸ | ALOX5 | P09917 | 4/20 | 1.00 |
| ▸ | CDK1 | P06493 | 13/20 | 0.83 |
| ▸ | CCNB1 | P14635 | 11/20 | 0.83 |
| ▸ | CCNB2 | O95067 | 10/20 | 0.83 |
| ▸ | CCNB3 | Q8WWL7 | 10/20 | 0.83 |
| ▸ | MEN1 | O00255 | 2/20 | 0.83 |
| ▸ | NPC1 | O15118 | 2/20 | 0.83 |
| ▸ | USP2 | O75604 | 2/20 | 0.83 |
| ▸ | LMNA | P02545 | 2/20 | 0.83 |
| ▸ | TP53 | P04637 | 2/20 | 0.83 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.83 |
| ▸ | MAPT | P10636 | 2/20 | 0.83 |
| ▸ | PKM | P14618 | 2/20 | 0.83 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.83 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.83 |
| ▸ | THPO | P40225 | 2/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29361130 | 0.91 | GSK3B (1.00) | CDK5R1GSK3BCDK5GSK3AALOX5 | |
| Indirubin-3-Monoxime SCHEMBL29354191 | 0.86 | CDK5R1 (1.00) | CDK5R1GSK3BCDK5GSK3AALOX5 | |
| SCHEMBL30319818 | 0.84 | GSK3B (0.83) | CDK5R1GSK3BCDK5GSK3AALOX5 | |
| SCHEMBL29484209 | 0.84 | GSK3B (1.00) | CDK5R1GSK3BCDK5GSK3AALOX5 | |
| SCHEMBL30141665 | 0.81 | CDK5R1 (1.00) | CDK5R1GSK3BCDK5GSK3AALOX5 | |
| SCHEMBL30309734 | 0.80 | CDK5R1 (1.00) | CDK5R1GSK3BCDK5GSK3AALOX5 | |
| SCHEMBL30278941 | 0.79 | GSK3B (1.00) | CDK5R1GSK3BCDK5GSK3AALOX5 | |
| SCHEMBL30295559 | 0.76 | CDK1 (1.00) | CDK5R1GSK3BCDK5GSK3AALOX5 | |
| SCHEMBL29924508 | 0.75 | GSK3B (0.72) | CDK5R1GSK3BCDK5GSK3AALOX5 | |
| SCHEMBL24487439 | 0.69 | ALOX5 (0.53) | CDK5R1GSK3BCDK5GSK3AALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112334131-B | Pharmaceutical composition comprising indirubin derivative as active ingredient | CK生物技术公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-115969814-A | Novel pharmaceutical formulations containing indirubin and derivatives thereof and methods of making and using the same | 法斯瑞斯公司 | 2023-04-18 | — | — | CN | disclosed |