Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 13/20 | 0.83 |
| ▸ | CDK5R1 | Q15078 | 12/20 | 0.83 |
| ▸ | CDK5 | Q00535 | 11/20 | 0.83 |
| ▸ | GSK3A | P49840 | 10/20 | 0.83 |
| ▸ | CDK1 | P06493 | 10/20 | 0.83 |
| ▸ | CCNB1 | P14635 | 9/20 | 0.83 |
| ▸ | CCNB2 | O95067 | 8/20 | 0.83 |
| ▸ | CCNB3 | Q8WWL7 | 8/20 | 0.83 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.77 |
| ▸ | CDK2 | P24941 | 5/20 | 0.77 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.77 |
| ▸ | CDK9 | P50750 | 2/20 | 0.77 |
| ▸ | FLT3 | P36888 | 5/20 | 0.74 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.74 |
| ▸ | STK17B | O94768 | 2/20 | 0.74 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.74 |
| ▸ | AURKA | O14965 | 2/20 | 0.74 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.74 |
| ▸ | AURKC | Q9UQB9 | 2/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Indirubin-3-Monoxime SCHEMBL29354191 | 0.86 | CDK5R1 (1.00) | GSK3BCDK5R1CDK5GSK3ACDK1 | |
| SCHEMBL30319828 | 0.84 | CDK5R1 (1.00) | GSK3BCDK5R1CDK5GSK3ACDK1 | |
| SCHEMBL29484209 | 0.84 | GSK3B (1.00) | GSK3BCDK5R1CDK5GSK3ACDK1 | |
| SCHEMBL30141665 | 0.81 | CDK5R1 (1.00) | GSK3BCDK5R1CDK5GSK3ACDK1 | |
| SCHEMBL30309734 | 0.80 | CDK5R1 (1.00) | GSK3BCDK5R1CDK5GSK3ACDK1 | |
| SCHEMBL29361130 | 0.78 | GSK3B (1.00) | GSK3BCDK5R1CDK5GSK3ACDK1 | |
| SCHEMBL29924508 | 0.75 | GSK3B (0.72) | GSK3BCDK5R1CDK5GSK3ACDK1 | |
| SCHEMBL30278941 | 0.74 | GSK3B (1.00) | GSK3BCDK5R1CDK5GSK3ACDK1 | |
| SCHEMBL6345762 | 0.69 | NPC1 (0.52) | GSK3BCDK5R1CDK5GSK3ACDK1 | |
| SCHEMBL6976558 | 0.68 | ALDH1A1 (0.72) | MEN1LMNAMAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115969814-A | Novel pharmaceutical formulations containing indirubin and derivatives thereof and methods of making and using the same | 法斯瑞斯公司 | 2023-04-18 | — | — | CN | disclosed |