Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5R1 | Q15078 | 17/20 | 1.00 |
| ▸ | GSK3B | P49841 | 16/20 | 1.00 |
| ▸ | CDK5 | Q00535 | 16/20 | 1.00 |
| ▸ | GSK3A | P49840 | 13/20 | 1.00 |
| ▸ | CDK1 | P06493 | 12/20 | 1.00 |
| ▸ | CCNB1 | P14635 | 10/20 | 1.00 |
| ▸ | CCNB2 | O95067 | 9/20 | 1.00 |
| ▸ | CCNB3 | Q8WWL7 | 9/20 | 1.00 |
| ▸ | ALOX5 | P09917 | 6/20 | 1.00 |
| ▸ | AURKB | Q96GD4 | 5/20 | 1.00 |
| ▸ | AURKC | Q9UQB9 | 5/20 | 1.00 |
| ▸ | FLT3 | P36888 | 4/20 | 1.00 |
| ▸ | AURKA | O14965 | 3/20 | 1.00 |
| ▸ | CCNE1 | P24864 | 3/20 | 1.00 |
| ▸ | CDK2 | P24941 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | NPC1 | O15118 | 2/20 | 1.00 |
| ▸ | USP2 | O75604 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | TP53 | P04637 | 2/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29361130 | 0.88 | GSK3B (1.00) | CDK5R1GSK3BCDK5GSK3ACDK1 | |
| SCHEMBL30319828 | 0.86 | CDK5R1 (1.00) | CDK5R1GSK3BCDK5GSK3ACDK1 | |
| SCHEMBL29484209 | 0.86 | GSK3B (1.00) | CDK5R1GSK3BCDK5GSK3ACDK1 | |
| SCHEMBL30319818 | 0.86 | GSK3B (0.83) | CDK5R1GSK3BCDK5GSK3ACDK1 | |
| SCHEMBL29924508 | 0.84 | GSK3B (0.72) | CDK5R1GSK3BCDK5GSK3ACDK1 | |
| SCHEMBL30278941 | 0.83 | GSK3B (1.00) | CDK5R1GSK3BCDK5GSK3ACDK1 | |
| SCHEMBL30141665 | 0.83 | CDK5R1 (1.00) | CDK5R1GSK3BCDK5GSK3ACDK1 | |
| SCHEMBL30309734 | 0.82 | CDK5R1 (1.00) | CDK5R1GSK3BCDK5GSK3ACDK1 | |
| SCHEMBL4064946 | 0.75 | CDK5 (0.60) | CDK5R1GSK3BCDK5GSK3ACDK1 | |
| SCHEMBL22443304 | 0.72 | PKM (0.58) | CDK5R1GSK3BCDK5GSK3ACDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 209 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4569090-A2 | METHODS AND COMPOSITIONS FOR GENERATING OLIGODENDROCYTE PROGENITOR CELLS | Trailhead Biosystems Inc. (US) | 2025-06-18 | — | — | EP | claimed |
| US-20240358767-A1 | STEM CELL DIFFERENTIATION AND CHEMICAL COMPOUNDS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2024-10-31 | — | — | US | claimed |
| EP-4430163-A2 | STEM CELL DIFFERENTIATION AND CHEMICAL COMPOUNDS | Vertex Pharmaceuticals Incorporated (US) | 2024-09-18 | — | — | EP | claimed |
| US-20240294879-A1 | STEM CELL DIFFERENTIATION AND POLYMERS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2024-09-05 | — | — | US | claimed |
| CN-114867849-B | Method for production of induced dopaminergic neuron progenitor cells using direct reprogramming | 韩国生命工学研究院 | 2024-07-12 | — | — | CN | claimed |
| WO-2024063818-A9 | METHODS AND COMPOSITIONS FOR GENERATING OLIGODENDROCYTE PROGENITOR CELLS | TRAILHEAD BIOSYSTEMS INC. (US) | 2024-05-23 | — | — | WO | claimed |
| CN-117802034-A | Method for spontaneous assembly of pluripotent stem cells into blastocysts and application thereof | 广州国家实验室 | 2024-04-02 | — | — | CN | claimed |
| WO-2024063818-A2 | METHODS AND COMPOSITIONS FOR GENERATING OLIGODENDROCYTE PROGENITOR CELLS | TRAILHEAD BIOSYSTEMS INC. (US) | 2024-03-28 | — | — | WO | claimed |
| CN-117757625-A | NK cell induction method based on porous material | 中国医学科学院输血研究所 | 2024-03-26 | — | — | CN | claimed |
| EP-4304617-A1 | STEM CELL DIFFERENTIATION AND POLYMERS | Vertex Pharmaceuticals Incorporated (US) | 2024-01-17 | — | — | EP | claimed |
| CN-116875535-A | Smog disease vascular organoid model and construction method thereof | 首都医科大学附属北京天坛医院 | 2023-10-13 | — | — | CN | claimed |
| CN-113072540-B | Indirubin-derived degradation agent and preparation and application thereof | 贵州医科大学 | 2023-07-14 | — | — | CN | claimed |
| US-20230174483-A1 | INDIRUBIN DERIVATIVES, AND USES THEREOF | CITY OF HOPE (US) | 2023-06-08 | — | — | US | claimed |
| CN-116200330-A | Method for down-regulating MAPK8 expression to induce reprogramming of cells into mammary epithelial cells | 广西壮族自治区人民医院 | 2023-06-02 | — | — | CN | claimed |
| WO-2023081884-A2 | STEM CELL DIFFERENTIATION AND CHEMICAL COMPOUNDS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-05-11 | — | — | WO | claimed |
| CN-115400213-A | Medical application and pharmaceutical composition of CDK1-USP29-Twist1 signal channel down-regulator | 暨南大学 | 2022-11-29 | — | — | CN | claimed |
| WO-2022192300-A1 | STEM CELL DIFFERENTIATION AND POLYMERS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-09-15 | — | — | WO | claimed |
| CN-114867849-A | Method for producing induced dopaminergic neuron progenitor cells using direct reprogramming | 韩国生命工学研究院 | 2022-08-05 | — | — | CN | claimed |
| CN-114712348-A | Application of indirubin-3' -oxime compound in preparation of antibacterial agent | 贵州医科大学 | 2022-07-08 | — | — | CN | claimed |
| EP-3987012-A1 | AUTOMATED METHOD FOR PREPARING RETINAL PIGMENT EPITHELIUM CELLS | Centre d'Etude des Cellules Souches (CECS) (FR) | 2022-04-27 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230174483-A1 | INDIRUBIN DERIVATIVES, AND USES THEREOF | HCCS, ABL1, MAP3K7 | CDK5R1 576/4885GSK3B 128/4885CDK5 321/4885 |
| US-20240358767-A1 | STEM CELL DIFFERENTIATION AND CHEMICAL COMPOUNDS | EBP, AKT3, PRKCD | CDK5R1 701/4885GSK3B 22/4885CDK5 409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.