Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 2/20 | 0.44 |
| ▸ | FBP1 | P09467 | 12/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25607565 | 1.00 | VCP (0.44) | VCPFBP1TGFBR1MEN1PSMD14 | |
| SCHEMBL29792042 | 0.72 | TGFBR1 (0.38) | TGFBR1L3MBTL1ALDH1A1S1PR4 | |
| SCHEMBL17429949 | 0.72 | TGFBR1 (0.38) | TGFBR1L3MBTL1ALDH1A1S1PR4 | |
| SCHEMBL16031383 | 0.71 | NFE2L2 (0.51) | VCPFBP1 | |
| SCHEMBL16031385 | 0.71 | NFE2L2 (0.51) | VCPFBP1 | |
| SCHEMBL17429951 | 0.70 | CCR1 (0.42) | TGFBR1MEN1KMT2A | |
| SCHEMBL25607532 | 0.69 | ALDH1A1 (0.51) | VCPFBP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL18590416 | 0.69 | FBP1 (0.46) | VCPFBP1MEN1PSMD14KMT2A | |
| SCHEMBL458238 | 0.68 | FBP1 (0.53) | VCPFBP1MEN1PSMD14KMT2A | |
| SCHEMBL458434 | 0.68 | FBP1 (0.53) | VCPFBP1MEN1PSMD14KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115867553-A | Diaminopyrazolo [1,5-a ] pyrimidine-6-carbonitrile compounds as adenosine 2A receptor and adenosine 2B receptor antagonists | 巴格沃克斯研究有限公司 | 2023-03-28 | — | — | CN | disclosed |