Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 8/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 7/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2523197 | 0.76 | CYP1A2 (0.39) | LMNA | |
| SCHEMBL27199355 | 0.66 | CYP1A2 (0.39) | LMNA | |
| SCHEMBL8795481 | 0.64 | ALDH1A1 (0.35) | LMNA | |
| SCHEMBL31569009 | 0.64 | MAPT (0.36) | LMNA | |
| SCHEMBL20400203 | 0.62 | NLRP3 (0.38) | LMNA | |
| SCHEMBL18215091 | 0.62 | MAPT (0.36) | — | |
| SCHEMBL16469649 | 0.62 | VCAM1 (0.36) | LMNA | |
| SCHEMBL2518380 | 0.62 | LMNA (0.39) | LMNA | |
| SCHEMBL16470062 | 0.62 | LRRK2 (0.40) | — | |
| SCHEMBL30908216 | 0.61 | MPO (0.37) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161494-A1 | NITROGEN-CONTAINING FUSED BICYCLIC COMPOUNDS AND THEIR USE AS UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 1 (USP1) INHIBITORS | KSQ Therapeutics, Inc. (US) | 2023-04-12 | — | — | EP | disclosed |